FNab08727

antibody from FineTest Biotech
Targeting: TLR4 ARMD10, CD284, hToll, TLR-4
Provider product page for FNab08727
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab08727 - Provider product page
Provider
FineTest Biotech
Product name
TLR4 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
toll-like receptor 4
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
TLR4 protein structure - FNab08727 shown in red.