4858

antibody from Cell Signaling Technology, Inc

Targeting: RPS6 S6

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

4858

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#4858, RRID:AB_916156

Product name

Phospho-S6 Ribosomal Protein (Ser235/236) (D57.2.2E) XP® Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Simian, Yeast, Other

Host

Rabbit

Storage

-20°C

References

Submitted references

Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity.

Thomé CH, dos Santos GA, Ferreira GA, Scheucher PS, Izumi C, Leopoldino AM, Simão AM, Ciancaglini P, de Oliveira KT, Chin A, Hanash SM, Falcão RP, Rego EM, Greene LJ, Faça VM
Molecular & cellular proteomics : MCP 2012 Dec;11(12):1898-912

---

Acetaminophen improves protein translational signaling in aged skeletal muscle.

Wu M, Liu H, Fannin J, Katta A, Wang Y, Arvapalli RK, Paturi S, Karkala SK, Rice KM, Blough ER
Rejuvenation research 2010 Oct;13(5):571-9

---

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.

Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM
Cancer cell 2009 Feb 3;15(2):148-59

---

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.

Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK
Nature medicine 2008 Dec;14(12):1351-6