S100A14

This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]

Description

S100 calcium binding protein A14

Tissue specificity

Group enriched (esophagus, vagina)

Subcell location

Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (153614255 - 153616986)

Ensembl ID

ENSG00000189334  (ver. 103.38)

Orthologs

Mouse S100a14: ENSMUSG00000042306

UniProt

Q9HCY8

neXtProt

NX_Q9HCY8

Human splice variants
Mouse splice variants

Protein structure