AFC-TAB-079

antibody from Creative Biolabs

Targeting: KDR CD309, FLK1, VEGFR, VEGFR2

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

AFC-TAB-079

Provider

Creative Biolabs

Product name

Afuco? Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced

Antibody type

Monoclonal

Description

This product is an ADCC enhanced antibody produced by our Afuco? platform. Recombinant monoclonal antibody to VEGF Receptor 2. Ramucirumab (IMC-1121B) is a fully human monoclonal antibody (IgG1) for the treatment of solid tumors. It is directed against the vascular endothelial growth factor receptor 2 (VEGFR2). By binding to VEGFR2 it works as a receptor antagonist blocking the binding of vascular endothelial growth factor (VEGF) to VEGFR2. VEGFR2 is known to mediate the majority of the downstream effects of VEGF in angiogenesis.

Reactivity

Human

Host

Human

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

Ramucirumab

Storage

Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.