Tissue expression
Cell line expression
Protein structure
CHTOP
Chromatin target of PRMT1C1orf77, DKFZP547E1010, FOP, SRAG
This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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Invitrogen Antibodies | PA5-44307 | Polyclonal |
WB
IP
IHC
OA |
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NovoPro Bioscience Inc. | 120570 | Monoclonal |
WB
ICC
IP
IHC |
||
OriGene | AM20824PU-L | Monoclonal |
WB
ICC
IP
IHC |
||
Aviva Systems Biology | ARP55300_P050 | Polyclonal |
WB
IP
IHC
|
||
Atlas Antibodies | HPA028647 | Polyclonal |
WB
ICC
IHC
|
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Recommended by provider