Ab101943
antibody from Aladdin Scientific Corporation
Targeting: EFNA1
ECKLG, EPLG1, GMAN, LERK1, TNFAIP4
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- Ab101943 - Provider product page
- Provider
- Aladdin Scientific Corporation
- Product name
- Recombinant Ephrin A1 Antibody
- Antibody type
- Recombinant
- Description
- Rabbit anti Human Ephrin A1 Antibody, Recombinant (R09-5N5), could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionPlays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cones.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
AA 25-45
- Antibody clone number
- R09-5N5
- Vial size
- 100μl,10μl,1ml,50μl
- Concentration
- 0,45 mg/ml
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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