AMM02086G

antibody from Leading Biology

Targeting: FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02086G

Provider

Leading Biology

Product name

FOXO3 / FOXO3A Antibody (clone 2H2)

Antibody type

Monoclonal

Description

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Reactivity

Human

Host

Mouse

Antibody clone number

2H2

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.