Antibody data
- Antibody Data
- Antigen structure
- References [86]
- Comments [0]
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- Product number
- 22034-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PTEN antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PTEN antibody (Cat. #22034-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
miR-638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
DEHP-elicited small extracellular vesicles miR-26a-5p promoted metastasis in nearby normal A549 cells.
Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes.
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Lapatinib‑induced inhibition of ovarian function is counteracted by the STAT3 pathway both in vivo and in vitro.
Targeting DNA to the endoplasmic reticulum efficiently enhances gene delivery and therapy.
SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
KIF15 contributes to cell proliferation and migration in breast cancer.
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Neuroprotective effects of miR-532-5p against ischemic stroke.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression.
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway.
Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1.
Evaluation of differentially expressed microRNAs in vitrified oocytes by next generation sequencing.
Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes.
Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons.
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma.
A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer.
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma.
MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN.
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
miR-217 Promotes Cardiac Hypertrophy and Dysfunction by Targeting PTEN.
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN.
Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis.
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer.
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway.
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice.
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model.
Best practice for PTEN gene and protein assessment in anatomic pathology.
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Yang R, Wen J, Yang T, Dai C, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Li Y, Xia M, Peng L, Liu H, Chen G, Wang C, Yuan D, Liu Y, Liu H
International journal of biological sciences 2021;17(13):3343-3355
International journal of biological sciences 2021;17(13):3343-3355
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
Wu Y, Zhang Z, Kou Z
Drug design, development and therapy 2021;15:2857-2868
Drug design, development and therapy 2021;15:2857-2868
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Wu R, Wang H, Huangfu J, Xiao R
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Yu C, Xiong C, Tang J, Hou X, Liu N, Bayliss G, Zhuang S
Theranostics 2021;11(6):2706-2721
Theranostics 2021;11(6):2706-2721
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Qian XL, Zhou F, Xu S, Jiang J, Chen ZP, Wang SK, Zuo Y, Ni C
Frontiers in oncology 2021;11:638537
Frontiers in oncology 2021;11:638537
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Dou L, Zhang Y
Frontiers in oncology 2021;11:614035
Frontiers in oncology 2021;11:614035
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Wu T, Wang G, Zeng X, Sun Z, Li S, Wang W, Yu B
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
miR-638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells.
Ma L, Zhang W, Jin Y, Bai X, Yu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1319
Experimental and therapeutic medicine 2021 Nov;22(5):1319
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Zhang Y, Sun J, Dong Y, Shen X, Zhang Z
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
DEHP-elicited small extracellular vesicles miR-26a-5p promoted metastasis in nearby normal A549 cells.
Qin Y, Zhang J, Avellán-Llaguno RD, Zhang X, Huang Q
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116005
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116005
Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes.
Zhao J, Song Y, Zeng Y, Chen L, Yan F, Chen A, Wu B, Wang Y
Scientific reports 2021 Jun 7;11(1):11966
Scientific reports 2021 Jun 7;11(1):11966
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Chen X, Xu T, Lv X, Zhang J, Liu S
Journal of ethnopharmacology 2021 Jun 28;274:113997
Journal of ethnopharmacology 2021 Jun 28;274:113997
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
Ha M, Huang X, Li L, Lu D, Liu C
The Science of the total environment 2021 Feb 25;757:143727
The Science of the total environment 2021 Feb 25;757:143727
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Lu Y, Hou K, Li M, Wu X, Yuan S
Frontiers in cell and developmental biology 2020;8:571297
Frontiers in cell and developmental biology 2020;8:571297
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L
Frontiers in neuroscience 2020;14:925
Frontiers in neuroscience 2020;14:925
Lapatinib‑induced inhibition of ovarian function is counteracted by the STAT3 pathway both in vivo and in vitro.
Liao Q, Feng X, Li X, Chen G, Chen J, Yang B, Li K, Ai J
Oncology reports 2020 Sep;44(3):1127-1135
Oncology reports 2020 Sep;44(3):1127-1135
Targeting DNA to the endoplasmic reticulum efficiently enhances gene delivery and therapy.
Qin B, Yuan X, Jiang M, Yin H, Luo Z, Zhang J, Zhu C, Li X, Shi Y, Luo L, Du Y, You J
Nanoscale 2020 Sep 21;12(35):18249-18262
Nanoscale 2020 Sep 21;12(35):18249-18262
SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN.
Shen X, Chen X, Wang J, Liu J, Wang Z, Hua Q, Wu Q, Su Y, He H, Hu Y, Meng Z, Xiong W, Zhu M
Experimental & molecular medicine 2020 Oct;52(10):1715-1729
Experimental & molecular medicine 2020 Oct;52(10):1715-1729
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
KIF15 contributes to cell proliferation and migration in breast cancer.
Gao X, Zhu L, Lu X, Wang Y, Li R, Jiang G
Human cell 2020 Oct;33(4):1218-1228
Human cell 2020 Oct;33(4):1218-1228
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Zhang Y, Guo J, Cai E, Cai J, Wen Y, Lu S, Li X, Han Q, Jiang J, Li T, Wang Z
Experimental cell research 2020 Oct 15;395(2):112218
Experimental cell research 2020 Oct 15;395(2):112218
MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Cao Z, Ji J, Wang FB, Kong C, Xu H, Xu YL, Chen X, Yu YW, Sun YH
Asian journal of andrology 2020 Nov-Dec;22(6):616-622
Asian journal of andrology 2020 Nov-Dec;22(6):616-622
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Wang Y, Wang R, Wu S, An J, Liang Y, Hou L, Zhang Z
Nanoscale 2020 May 7;12(17):9392-9403
Nanoscale 2020 May 7;12(17):9392-9403
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D
Journal of food science 2020 Jun;85(6):1872-1890
Journal of food science 2020 Jun;85(6):1872-1890
Neuroprotective effects of miR-532-5p against ischemic stroke.
Mu J, Cheng X, Zhong S, Chen X, Zhao C
Metabolic brain disease 2020 Jun;35(5):753-763
Metabolic brain disease 2020 Jun;35(5):753-763
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression.
Wang Z, Yu W, Qiang Y, Xu L, Ma F, Ding P, Shi L, Chang W, Mei Y, Ma X
Molecular therapy oncolytics 2020 Jun 26;17:547-561
Molecular therapy oncolytics 2020 Jun 26;17:547-561
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Tan Y, Yin L, Sun Z, Shao S, Chen W, Man X, Du Y, Chen Y
International journal of biological macromolecules 2020 Jun 15;153:349-356
International journal of biological macromolecules 2020 Jun 15;153:349-356
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
Dai H, Li M, Yang W, Sun X, Wang P, Wang X, Su J, Wang X, Hu X, Zhao M
Aging 2020 Jun 12;12(12):11717-11731
Aging 2020 Jun 12;12(12):11717-11731
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Yan Z, Zang B, Gong X, Ren J, Wang R
Life sciences 2020 Jan 15;241:117118
Life sciences 2020 Jan 15;241:117118
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
Zhao J, Han Y, Wang Z, Zhang R, Wang G, Mao Y
Biotechnology letters 2020 Dec;42(12):2749-2758
Biotechnology letters 2020 Dec;42(12):2749-2758
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Shi WJ, Liu H, Ge YF, Wu D, Tan YJ, Shen YC, Wang H, Xu H
Cytokine 2020 Dec;136:155286
Cytokine 2020 Dec;136:155286
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Yu M, Liu W, Li J, Lu J, Lu H, Jia W, Liu F
Stem cell research & therapy 2020 Aug 12;11(1):350
Stem cell research & therapy 2020 Aug 12;11(1):350
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, Qi Y, Xu J, Yang Y, Song W, He X, Liu S, Yuan X, Yin W, He Y, Pan W, Wei L, Zhang J
BioMed research international 2019;2019:3235021
BioMed research international 2019;2019:3235021
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Guo J, Li Y, Duan H, Yuan L
Cancer cell international 2019;19:156
Cancer cell international 2019;19:156
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
Dong C, Liu X, Wang H, Li J, Dai L, Li J, Xu Z
OncoTargets and therapy 2019;12:1947-1956
OncoTargets and therapy 2019;12:1947-1956
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470
Pediatric research 2019 Oct;86(4):460-470
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, Zheng L, Zhou X, Fu H, Zhou D, Chen Y
International immunopharmacology 2019 Oct;75:105768
International immunopharmacology 2019 Oct;75:105768
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W
Environment international 2019 Oct;131:104943
Environment international 2019 Oct;131:104943
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway.
Liu G, Zhou J, Dong M
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1.
Xu Y, Zhang G, Zou C, Gong Z, Wang S, Liu J, Ma G, Liu X, Zhang W, Jiang P
Journal of cellular physiology 2019 Jul;234(7):11999-12010
Journal of cellular physiology 2019 Jul;234(7):11999-12010
Evaluation of differentially expressed microRNAs in vitrified oocytes by next generation sequencing.
Li J, Yang X, Liu F, Song Y, Liu Y
The international journal of biochemistry & cell biology 2019 Jul;112:134-140
The international journal of biochemistry & cell biology 2019 Jul;112:134-140
Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes.
Shen F, Xiong Z, Kong J, Wang L, Cheng Y, Jin J, Huang Z
Toxicology letters 2019 Jan;300:105-115
Toxicology letters 2019 Jan;300:105-115
Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons.
Wang S, Huang Y, Yan Y, Zhou H, Wang M, Liao L, Wang Z, Chen D, Ji D, Xia X, Liu F, Huang J, Xiong K
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2019 Jan;221:57-67
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2019 Jan;221:57-67
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Shen X, Zhong J, Yu P, Zhao Q, Huang T
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma.
Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu CR, Li L, Kuang D, Ye F
Current medical science 2019 Dec;39(6):929-937
Current medical science 2019 Dec;39(6):929-937
A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer.
Jin G, Liu Y, Zhang J, Bian Z, Yao S, Fei B, Zhou L, Yin Y, Huang Z
Cancer chemotherapy and pharmacology 2019 Aug;84(2):315-325
Cancer chemotherapy and pharmacology 2019 Aug;84(2):315-325
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma.
Sun B, Zhao X, Ming J, Liu X, Liu D, Jiang C
Oncogene 2019 Aug;38(33):6142-6157
Oncogene 2019 Aug;38(33):6142-6157
MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN.
He T, Sun Y, Zhang Y, Zhao S, Zheng Y, Hao G, Shi Y
Reproductive biology and endocrinology : RB&E 2019 Aug 17;17(1):68
Reproductive biology and endocrinology : RB&E 2019 Aug 17;17(1):68
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
He Y, Khan M, Yang J, Yao M, Yu S, Gao H
International journal of medical sciences 2018;15(8):832-839
International journal of medical sciences 2018;15(8):832-839
miR-217 Promotes Cardiac Hypertrophy and Dysfunction by Targeting PTEN.
Nie X, Fan J, Li H, Yin Z, Zhao Y, Dai B, Dong N, Chen C, Wang DW
Molecular therapy. Nucleic acids 2018 Sep 7;12:254-266
Molecular therapy. Nucleic acids 2018 Sep 7;12:254-266
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Mu Z, Sun Q
Molecular medicine reports 2018 Nov;18(5):4603-4610
Molecular medicine reports 2018 Nov;18(5):4603-4610
LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN.
Gao Q, Tang L, Wu L, Li K, Wang H, Li W, Wu J, Li M, Wang S, Zhao L
Cell death & disease 2018 Mar 12;9(3):393
Cell death & disease 2018 Mar 12;9(3):393
Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X, Su Q
Journal of experimental & clinical cancer research : CR 2018 Mar 12;37(1):54
Journal of experimental & clinical cancer research : CR 2018 Mar 12;37(1):54
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Zhu X, Li Z, Li T, Long F, Lv Y, Liu L, Liu X, Zhan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Wang Y, Zhang S, Liu J, Fang B, Yao J, Cheng B
Molecular medicine reports 2018 Jul;18(1):911-919
Molecular medicine reports 2018 Jul;18(1):911-919
Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis.
Zhao XC, Yang SH, Yan YQ, Zhang X, Zhang L, Jiao B, Jiang S, Yu ZB
BMC medical genomics 2018 Jul 11;11(1):59
BMC medical genomics 2018 Jul 11;11(1):59
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Zhao Q, Guan J, Zhang Z, Lv J, Wang Y, Liu L, Zhou Q, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
Liao B, Zhou H, Liang H, Li C
International journal of oncology 2017 Nov;51(5):1449-1459
International journal of oncology 2017 Nov;51(5):1449-1459
MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer.
Li N, Miao Y, Shan Y, Liu B, Li Y, Zhao L, Jia L
Cell death & disease 2017 May 18;8(5):e2796
Cell death & disease 2017 May 18;8(5):e2796
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Wang Y, Chen F, Yang Z, Zhao M, Zhang S, Gao Y, Feng J, Yang G, Zhang W, Ye L, Zhang X
Scientific reports 2017 May 18;7(1):2070
Scientific reports 2017 May 18;7(1):2070
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Lu J, Xie L, Liu C, Zhang Q, Sun S
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Xu J, Liu D, Niu H, Zhu G, Xu Y, Ye D, Li J, Zhang Q
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, Wang K, Bao J, Liang Y, Chen M, Li P, Su H, Lee SM, Liu K, Wan JB, He C
Scientific reports 2017 Jan 23;7:41082
Scientific reports 2017 Jan 23;7:41082
MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway.
Miao Y, Zheng W, Li N, Su Z, Zhao L, Zhou H, Jia L
Scientific reports 2017 Feb 6;7:41942
Scientific reports 2017 Feb 6;7:41942
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Chen L, Zhang F, Sheng XG, Zhang SQ, Chen YT, Liu BW
Oncology reports 2016 Oct;36(4):2135-41
Oncology reports 2016 Oct;36(4):2135-41
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Mizunuma M, Yokoyama Y, Futagami M, Horie K, Watanabe J, Mizunuma H
Heliyon 2016 May;2(5):e00116
Heliyon 2016 May;2(5):e00116
Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice.
Huang W, Tian SS, Hang PZ, Sun C, Guo J, Du ZM
Molecular therapy. Nucleic acids 2016 Mar 15;5:e296
Molecular therapy. Nucleic acids 2016 Mar 15;5:e296
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, Du H, Wang B, Zhang Y, Sun D, Nan Y
FEBS letters 2016 Aug;590(16):2709-24
FEBS letters 2016 Aug;590(16):2709-24
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model.
Eritja N, Santacana M, Maiques O, Gonzalez-Tallada X, Dolcet X, Matias-Guiu X
Methods (San Diego, Calif.) 2015 May;77-78:31-40
Methods (San Diego, Calif.) 2015 May;77-78:31-40
Best practice for PTEN gene and protein assessment in anatomic pathology.
Carvalho KC, Maia BM, Omae SV, Rocha AA, Covizzi LP, Vassallo J, Rocha RM, Soares FA
Acta histochemica 2014 Jan;116(1):25-31
Acta histochemica 2014 Jan;116(1):25-31
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Feng Y, Liu J, Kang Y, He Y, Liang B, Yang P, Yu Z
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33:67
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33:67
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