BS8358

antibody from Bioworld Technology, Inc
Targeting: PIKFYVE FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29
Provider product page for BS8358
Western blot
Immunohistochemistry

Antibody data

Product number
BS8358 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PIP5K3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PIP5K3.
Description
The PIP5K family is divided into type I, type II and type III proteins, each of which phosphorylates distinct substrates. The PIP5K proteins contain an activation loop which determines their enzymatic specificity and subcellular targeting. Phosphatidylinositol-4-phosphate-5-kinase, also known as PIP5KIII or PIP5K3, synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. Located in the membrane of the endosome, PIP5KIII contains an FYVE-type zinc finger and catalyzes the rate-limiting step in the production of phosphatidylinositol, a phospholipid that plays a role in Actin dynamics. Defects in the gene encoding PIP5KIII lead to corneal fleck dystrophy (CFD), an autosomal disorder in which small white flecks are found throughout the corneal stroma..
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PIKFYVE protein structure - BS8358 shown in red.