11149-1-AP

antibody from Proteintech Group

Targeting: EIF4E EIF4E1, EIF4EL1, EIF4F

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

11149-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11149-1-AP, RRID:AB_2097686

Product name

CBP,EIF4E antibody

Antibody type

Polyclonal

Description

KD/KO validated CBP,EIF4E antibody (Cat. #11149-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.

Zhang C, Shen L, Zhu Y, Xu R, Deng Z, Liu X, Ding Y, Wang C, Shi Y, Bei L, Wei D, Thorne RF, Zhang XD, Yu L, Chen S
Theranostics 2021;11(6):2691-2705

---

Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.

Sun Y, Zhang H, Wu Z, Yu X, Yin Y, Qian S, Wang Z, Huang J, Wang W, Liu T, Xue W, Chen G
ACS chemical neuroscience 2021 Sep 15;12(18):3387-3396

---

Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.

Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;

---

Proteomic analysis of Trypanosoma cruzi spliceosome complex.

Barbosa RL, da Cunha JPC, Menezes AT, Melo RFP, Elias MC, Silber AM, Coltri PP
Journal of proteomics 2020 Jul 15;223:103822

---

The Natural Compound Homoharringtonine Presents Broad Antiviral Activity In Vitro and In Vivo.

Dong HJ, Wang ZH, Meng W, Li CC, Hu YX, Zhou L, Wang XJ
Viruses 2018 Nov 1;10(11)

---

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function.

Du Y, Hou G, Zhang H, Dou J, He J, Guo Y, Li L, Chen R, Wang Y, Deng R, Huang J, Jiang B, Xu M, Cheng J, Chen GQ, Zhao X, Yu J
Nucleic acids research 2018 Jun 1;46(10):5195-5208

---

Multifunctional viral protein γ34.5 manipulates nucleolar protein NOP53 for optimal viral replication of HSV-1.

Meng W, Han SC, Li CC, Dong HJ, Wang XJ
Cell death & disease 2018 Jan 24;9(2):103

---

HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc.

Li Y, Wang Z, Shi H, Li H, Li L, Fang R, Cai X, Liu B, Zhang X, Ye L
Cancer research 2016 Jan 15;76(2):293-304

---

Pemetrexed induces G1 phase arrest and apoptosis through inhibiting Akt activation in human non small lung cancer cell line A549.

Wu DM, Zhang P, Xu GC, Tong AP, Zhou C, Lang JY, Wang CT
Asian Pacific journal of cancer prevention : APJCP 2015;16(4):1507-13

---

Identification of the receptor tyrosine kinases (RTKs)-oriented functional targets of miR-206 by an antibody-based protein array.

Cui Y, Xie S, Luan J, Zhou X, Han J
FEBS letters 2015 Jul 22;589(16):2131-5

---

mTOR inhibitor AZD8055 inhibits proliferation and induces apoptosis in laryngeal carcinoma.

Zhao L, Teng B, Wen L, Feng Q, Wang H, Li N, Wang Y, Liang Z
International journal of clinical and experimental medicine 2014;7(2):337-47

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HEK-293 cells were subjected to SDS PAGE followed by western blot with 11149-1-AP(EIF4E antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using EIF4E antibody 11149-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 11149-1-AP(EIF4E antibody) at dilution of 1:100 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 11149-1-AP(EIF4E antibody) at dilution of 1:100 (under 40x lens)

Sample type

tissue