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- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16166-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16166-1-AP, RRID:AB_2116779
- Product name
- HDAC5-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HDAC5-specific antibody (Cat. #16166-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references EGCG prevents pressure overload‑induced myocardial remodeling by downregulating overexpression of HDAC5 in mice.
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
Repeated stress exposure in mid-adolescence attenuates behavioral, noradrenergic, and epigenetic effects of trauma-like stress in early adult male rats.
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Antithetical regulation of α-myosin heavy chain between fetal and adult heart failure though shuttling of HDAC5 regulating YY-1 function.
Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy.
HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury.
Han X, Peng C, Huang L, Luo X, Mao Q, Wu S, Zhang H
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy.
An J, Zhang X, Jia K, Zhang C, Zhu L, Cheng M, Li F, Zhao S, Hao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111062
Repeated stress exposure in mid-adolescence attenuates behavioral, noradrenergic, and epigenetic effects of trauma-like stress in early adult male rats.
Chaby LE, Sadik N, Burson NA, Lloyd S, O'Donnel K, Winters J, Conti AC, Liberzon I, Perrine SA
Scientific reports 2020 Oct 21;10(1):17935
Scientific reports 2020 Oct 21;10(1):17935
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
Feng S, Zhang L, Liu X, Li G, Zhang B, Wang Z, Zhang H, Ma H
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
Antithetical regulation of α-myosin heavy chain between fetal and adult heart failure though shuttling of HDAC5 regulating YY-1 function.
Fang J, Li Y, Zhou K, Hua Y, Wang C, Mu D
Cardiovascular toxicology 2015 Apr;15(2):147-56
Cardiovascular toxicology 2015 Apr;15(2):147-56
Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy.
Wang X, Liu J, Zhen J, Zhang C, Wan Q, Liu G, Wei X, Zhang Y, Wang Z, Han H, Xu H, Bao C, Song Z, Zhang X, Li N, Yi F
Kidney international 2014 Oct;86(4):712-25
Kidney international 2014 Oct;86(4):712-25
HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury.
He M, Zhang B, Wei X, Wang Z, Fan B, Du P, Zhang Y, Jian W, Chen L, Wang L, Fang H, Li X, Wang PA, Yi F
Journal of cellular and molecular medicine 2013 Apr;17(4):531-42
Journal of cellular and molecular medicine 2013 Apr;17(4):531-42
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16166-1-AP(HDAC5-specific antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16166-1-AP(HDAC5-specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HDAC5-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human HDAC5-specific. This antibody recognizes human, mouse, rat antigen. The HDAC5-specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
