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antibody from Atlas Antibodies
Targeting: GPBAR1
BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA062890 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA062890, RRID:AB_2684896
- Product name
- Anti-GPBAR1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human GPBAR1, Gene description: G protein-coupled bile acid receptor 1, Alternative Gene Names: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5, Validated applications: IHC, Uniprot ID: Q8TDU6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.05 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Elevated bile acids are associated with left ventricular structural changes in biliary atresia
The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice
G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
Virk M, Mian M, Bashir D, Wilkes J, Schlingman T, Flores S, Kennedy C, Lam F, Arikan A, Nguyen T, Mysore K, Galvan N, Coss-Bu J, Karpen S, Harpavat S, Desai M
Hepatology Communications 2023;7(5)
Hepatology Communications 2023;7(5)
The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice
Wang X, Xie C, Libby A, Ranjit S, Levi J, Myakala K, Bhasin K, Jones B, Orlicky D, Takahashi S, Dvornikov A, Kleiner D, Hewitt S, Adorini L, Kopp J, Krausz K, Rosenberg A, McManaman J, Robertson C, Ir D, Frank D, Luo Y, Gonzalez F, Gratton E, Levi M
Journal of Biological Chemistry 2022;298(11):102530
Journal of Biological Chemistry 2022;298(11):102530
G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
Wang X, Edelstein M, Gafter U, Qiu L, Luo Y, Dobrinskikh E, Lucia S, Adorini L, D’Agati V, Levi J, Rosenberg A, Kopp J, Gius D, Saleem M, Levi M
Journal of the American Society of Nephrology 2016;27(5):1362-1378
Journal of the American Society of Nephrology 2016;27(5):1362-1378
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human gallbladder and skeletal muscle tissues using HPA062890 antibody. Corresponding GPBAR1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
