Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 317202 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#317202, RRID:AB_571931
- Product name
- Purified anti-human CD352 (NTB-A)
- Antibody type
- Monoclonal
- Antigen
- Recombinant extracellular domain of NTB-A
- Description
- NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones.
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts.
Uzana R, Eisenberg G, Sagi Y, Frankenburg S, Merims S, Amariglio N, Yefenof E, Peretz T, Machlenkin A, Lotem M
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):632-40
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):632-40
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts.
Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D, Barker E
Blood 2007 Aug 15;110(4):1207-14
Blood 2007 Aug 15;110(4):1207-14
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with purified NT-7, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated