FNab08335

antibody from FineTest Biotech

Targeting: STK36 FU, KIAA1278

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Immunoprecipitation

Immunohistochemistry

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Validation data

Product number: FNab08335 - Provider product page
Provider: FineTest Biotech
Product name: STK36 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: serine/threonine kinase 36, fused h omolog(Drosophila)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

STK36 protein structure - FNab08335 shown in red.