Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14739-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14739-1-AP, RRID:AB_2089276
- Product name
- CYP27A1 antibody
- Antibody type
- Polyclonal
- Description
- CYP27A1 antibody (Cat. #14739-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Chemical profile of Swertia mussotii Franch and its potential targets against liver fibrosis revealed by cross-platform metabolomics.
Dolomiaea souliei ethyl acetate extract protected against α-naphthylisothiocyanate-induced acute intrahepatic cholestasis through regulation of farnesoid x receptor-mediated bile acid metabolism.
Dehydrodiconiferyl alcohol, a lignan from Herpetospermum pedunculosum, alleviates cholestasis by activating pathways associated with the farnesoid X receptor.
Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.
Increased maternal and fetal cholesterol efflux capacity and placental CYP27A1 expression in preeclampsia.
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats.
Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina.
Zhang Y, Zhou Q, Ding X, Ma J, Tan G
Journal of ethnopharmacology 2021 Jun 28;274:114051
Journal of ethnopharmacology 2021 Jun 28;274:114051
Dolomiaea souliei ethyl acetate extract protected against α-naphthylisothiocyanate-induced acute intrahepatic cholestasis through regulation of farnesoid x receptor-mediated bile acid metabolism.
Meng F, Zong W, Wei X, Tao Y, Wang G, Liao Z, Chen M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153588
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153588
Dehydrodiconiferyl alcohol, a lignan from Herpetospermum pedunculosum, alleviates cholestasis by activating pathways associated with the farnesoid X receptor.
Wei X, Ma Y, Dong Z, Wang G, Lan X, Liao Z, Chen M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153378
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153378
Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.
Teng S, Li YE, Yang M, Qi R, Huang Y, Wang Q, Zhang Y, Chen S, Li S, Lin K, Cao Y, Ji Q, Gu Q, Cheng Y, Chang Z, Guo W, Wang P, Garcia-Bassets I, Lu ZJ, Wang D
Cell research 2020 Jan;30(1):34-49
Cell research 2020 Jan;30(1):34-49
Increased maternal and fetal cholesterol efflux capacity and placental CYP27A1 expression in preeclampsia.
Mistry HD, Kurlak LO, Mansour YT, Zurkinden L, Mohaupt MG, Escher G
Journal of lipid research 2017 Jun;58(6):1186-1195
Journal of lipid research 2017 Jun;58(6):1186-1195
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, Zhao R
Nutrients 2016 Oct 18;8(10)
Nutrients 2016 Oct 18;8(10)
Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats.
Jia X, Naito H, Yetti H, Tamada H, Kitamori K, Hayashi Y, Wang D, Yanagiba Y, Wang J, Ikeda K, Yamori Y, Nakajima T
Digestive diseases and sciences 2013 Aug;58(8):2212-22
Digestive diseases and sciences 2013 Aug;58(8):2212-22
Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina.
Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O
BMC ophthalmology 2011 Aug 18;11:22
BMC ophthalmology 2011 Aug 18;11:22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 14739-1-AP(CYP27A1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14739-1-AP(CYP27A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CYP27A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CYP27A1. This antibody recognizes human,mouse,rat antigen. The CYP27A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.