Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17856-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- USP21 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP21 antibody (Cat. #17856-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study.
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression.
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Hsu FS, Lin WC, Kuo KL, Chiu YL, Hsu CH, Liao SM, Dong JR, Liu SH, Chang SC, Yang SP, Chen YT, Chang RJ, Huang KH
International journal of molecular sciences 2021 Oct 28;22(21)
International journal of molecular sciences 2021 Oct 28;22(21)
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression.
Gao W, Li G, Zhao S, Wang H, Huan C, Zheng B, Jiang C, Zhang W
Journal of virology 2021 Jun 10;95(13):e0046021
Journal of virology 2021 Jun 10;95(13):e0046021
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
Liu Z, Dagley LF, Shield-Artin K, Young SN, Bankovacki A, Wang X, Tang M, Howitt J, Stafford CA, Nachbur U, Fitzgibbon C, Garnish SE, Webb AI, Komander D, Murphy JM, Hildebrand JM, Silke J
The EMBO journal 2021 Dec 1;40(23):e103718
The EMBO journal 2021 Dec 1;40(23):e103718
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Li W, Cui K, Prochownik EV, Li Y
Cell death & disease 2018 May 1;9(5):482
Cell death & disease 2018 May 1;9(5):482
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The USP21 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USP21. This antibody recognizes human antigen. The USP21 antibody has been validated for the following applications: ELISA, WB, IHC analysis.