Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2842145 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Antibody clone number
- RB3367
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.
PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2.
The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia.
Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation.
Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.
FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression.
Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human.
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
Chen X, Xie W, Gu P, Cai Q, Wang B, Xie Y, Dong W, He W, Zhong G, Lin T, Huang J
Scientific reports 2015 Feb 6;5:8293
Scientific reports 2015 Feb 6;5:8293
PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2.
Lee JG, Kay EP
Investigative ophthalmology & visual science 2011 Jan 21;52(1):417-26
Investigative ophthalmology & visual science 2011 Jan 21;52(1):417-26
The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia.
Nakamura S, Hirano I, Okinaka K, Takemura T, Yokota D, Ono T, Shigeno K, Shibata K, Fujisawa S, Ohnishi K
Carcinogenesis 2010 Nov;31(11):2012-21
Carcinogenesis 2010 Nov;31(11):2012-21
Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation.
Takemura T, Nakamura S, Yokota D, Hirano I, Ono T, Shigeno K, Fujisawa S, Ohnishi K
The Journal of biological chemistry 2010 Feb 26;285(9):6585-94
The Journal of biological chemistry 2010 Feb 26;285(9):6585-94
Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.
Nakamura S, Yamashita M, Yokota D, Hirano I, Ono T, Fujie M, Shibata K, Niimi T, Suyama T, Maddali K, Asai K, Yamashita J, Iguchi Y, Ohnishi K
Investigational new drugs 2010 Aug;28(4):381-91
Investigational new drugs 2010 Aug;28(4):381-91
FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression.
Petrovic V, Costa RH, Lau LF, Raychaudhuri P, Tyner AL
The Journal of biological chemistry 2008 Jan 4;283(1):453-60
The Journal of biological chemistry 2008 Jan 4;283(1):453-60
Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human.
Bièche I, Manceau V, Curmi PA, Laurendeau I, Lachkar S, Leroy K, Vidaud D, Sobel A, Maucuer A
Brain research. Molecular brain research 2003 May 26;114(1):55-64
Brain research. Molecular brain research 2003 May 26;114(1):55-64
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG
The EMBO journal 2002 Jul 1;21(13):3390-401
The EMBO journal 2002 Jul 1;21(13):3390-401
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC