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- Antibody Data
- Antigen structure
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- Product number
- abx029346 - Provider product page
- Provider
- Abbexa
- Product name
- Integral Membrane Protein 2C (ITM2C) Antibody
- Antibody type
- Polyclonal
- Description
- Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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