Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
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Validation data
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- Product number
- ABIN499211 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ADAM Metallopeptidase Domain 10 (ADAM10) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Human ADAM10 (C-Terminus) Peptide (AP30017CP-N)
- Description
- Ion exchange chromatography
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Processing of the notch ligand delta by the metalloprotease Kuzbanian.
Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases.
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis.
Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types.
Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S
Science (New York, N.Y.) 1999 Jan 1;283(5398):91-4
Science (New York, N.Y.) 1999 Jan 1;283(5398):91-4
Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases.
Rosendahl MS, Ko SC, Long DL, Brewer MT, Rosenzweig B, Hedl E, Anderson L, Pyle SM, Moreland J, Meyers MA, Kohno T, Lyons D, Lichenstein HS
The Journal of biological chemistry 1997 Sep 26;272(39):24588-93
The Journal of biological chemistry 1997 Sep 26;272(39):24588-93
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis.
Pan D, Rubin GM
Cell 1997 Jul 25;90(2):271-80
Cell 1997 Jul 25;90(2):271-80
Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types.
Howard L, Lu X, Mitchell S, Griffiths S, Glynn P
The Biochemical journal 1996 Jul 1;317 ( Pt 1):45-50
The Biochemical journal 1996 Jul 1;317 ( Pt 1):45-50
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ADAM10 in Jurkat whole cell lysate with AP30017PU-N ADAM10 antibody at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence staining of K562 cells using AP30017PU-N ADAM10 antibody at 10 ?g/ml.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry staining of K562 cells using AP30017PU-N ADAM10 antibody at 2 ?g/ml.