MAB3345

antibody from Abnova Corporation

Targeting: ABCB1 ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1

No application information provided.

Antibody Data

Product number

MAB3345

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB3345, RRID:AB_10628391

Product name

ABCB1 monoclonal antibody, clone MRK16

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against native ABCB1.

Isotype

IgG

Antibody clone number

MRK16

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers.

Fung KL, Kapoor K, Pixley JN, Talbert DJ, Kwit AD, Ambudkar SV, Gottesman MM
Drug metabolism and disposition: the biological fate of chemicals 2016 Feb;44(2):180-8

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Synthesis and characterization of the anticancer and metal binding properties of novel pyrimidinylhydrazone derivatives.

Pape VF, Türk D, Szabó P, Wiese M, Enyedy EA, Szakács G
Journal of inorganic biochemistry 2015 Mar;144:18-30

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Digoxin net secretory transport in bronchial epithelial cell layers is not exclusively mediated by P-glycoprotein/MDR1.

Hutter V, Chau DY, Hilgendorf C, Brown A, Cooper A, Zann V, Pritchard DI, Bosquillon C
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2014 Jan;86(1):74-82

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The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.

Meszaros P, Hummel I, Klappe K, Draghiciu O, Hoekstra D, Kok JW
Biochimica et biophysica acta 2013 Feb;1828(2):340-51

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P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels.

Anderle P, Niederer E, Rubas W, Hilgendorf C, Spahn-Langguth H, Wunderli-Allenspach H, Merkle HP, Langguth P
Journal of pharmaceutical sciences 1998 Jun;87(6):757-62

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Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations.

Beck WT, Grogan TM, Willman CL, Cordon-Cardo C, Parham DM, Kuttesch JF, Andreeff M, Bates SE, Berard CW, Boyett JM, Brophy NA, Broxterman HJ, Chan HS, Dalton WS, Dietel M, Fojo AT, Gascoyne RD, Head D, Houghton PJ, Srivastava DK, Lehnert M, Leith CP, Paietta E, Pavelic ZP, Weinstein R
Cancer research 1996 Jul 1;56(13):3010-20

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In vivo imaging and specific targeting of P-glycoprotein expression in multidrug resistant nude mice xenografts with [125I]MRK-16 monoclonal antibody.

Scott AM, Rosa E, Mehta BM, Divgi CR, Finn RD, Biedler JL, Tsuruo T, Kalaigian H, Larson SM
Nuclear medicine and biology 1995 May;22(4):497-504