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Protein structure
COPS8
COP9 signalosome subunit 8COP9, CSN8, MGC1297, SGN8
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  10089-2-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 10089-2-AP |
Polyclonal |
WB
IP
IHC
OA
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| Enzo Life Sciences | ALX-210-922-C050 |
1 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN499656 |
5 references | Polyclonal |
WB
EL
|
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| NovoPro Bioscience Inc. | 109466 |
Polyclonal |
WB
EL
IHC
|
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