ALX-801-039-C200

antibody from Enzo Life Sciences

Targeting: ABCC4 EST170205, MOAT-B, MOATB, MRP4

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ALX-801-039-C200

Provider

Enzo Life Sciences

Product name

MRP4 monoclonal antibody (M4I-80)

Antibody type

Monoclonal

Antigen

Recombinant protein fragment

Reactivity

Human, Mouse

Host

Rat

Isotype

IgG

Antibody clone number

M4I-80

Vial size

200 μg

Storage

-20°C

References

Submitted references

Increased serum bile acid concentration following low-dose chronic administration of thioacetamide in rats, as evidenced by metabolomic analysis.

Jeong ES, Kim G, Shin HJ, Park SM, Oh JH, Kim YB, Moon KS, Choi HK, Jeong J, Shin JG, Kim DH
Toxicology and applied pharmacology 2015 Oct 15;288(2):213-22

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Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 May 1;15(9):3084-93

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Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Dec 15;14(24):8152-60

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Mrp4 confers resistance to topotecan and protects the brain from chemotherapy.

Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD
Molecular and cellular biology 2004 Sep;24(17):7612-21