Tissue expression
Cell line expression
Protein structure
ATP6V1G3
ATPase H+ transporting V1 subunit G3ATP6G3, Vma10
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | 19523-1-AP | Polyclonal |
WB
IP
IHC
OA |
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Proteintech Group | 19523-1-AP | Polyclonal |
WB
EL
IP
IHC |
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NovoPro Bioscience Inc. | 108316 | Polyclonal |
WB
EL
IP
IHC |
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antibodies-online | ABIN4282337 | Polyclonal |
WB
ICC
IHC
|
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Cusabio Biotech Co., Ltd | CSB-PA002410GA01HU | Polyclonal |
WB
EL
IHC
|
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