Antibody data
- Antibody Data
- Antigen structure
- References [138]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- 21829-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21829-1-AP, RRID:AB_10837075
- Product name
- GLUT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLUT1 antibody (Cat. #21829-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gestational Diabetes Mellitus-Associated Hyperglycemia Impairs Glucose Transporter 3 Trafficking in Trophoblasts Through the Downregulation of AMP-Activated Protein Kinase.
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Up-Regulation of Glycogen Synthesis and Degradation Enzyme Level Maintained Myocardial Glycogen in Huddling Brandt's Voles Under Cool Environments.
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Activated Pancreatic Stellate Cells Enhance the Warburg Effect to Cause the Malignant Development in Chronic Pancreatitis.
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis.
Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase.
MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis.
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
Microenvironment Analysis of Prognosis and Molecular Signature of Immune-Related Genes in Lung Adenocarcinoma.
Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway.
Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway.
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Glucose-Lipopeptide Conjugates Reveal the Role of Glucose Modification Position in Complexation and the Potential of Malignant Melanoma Therapy.
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer.
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Long Noncoding RNA MIR210HG Promotes the Warburg Effect and Tumor Growth by Enhancing HIF-1α Translation in Triple-Negative Breast Cancer.
Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model.
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.
Platelet-rich plasma improves chronic inflammatory pain by inhibiting PKM2-mediated aerobic glycolysis in astrocytes.
Vitamin K2 promotes PI3K/AKT/HIF-1α-mediated glycolysis that leads to AMPK-dependent autophagic cell death in bladder cancer cells.
The effect of high glucose on the biological characteristics of nucleus pulposus-derived mesenchymal stem cells.
Immunohistochemistry and gene expression of GLUT1, RUNX2 and MTOR in reparative dentinogenesis.
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Decreased glucose bioavailability and elevated aspartate metabolism in prostate cancer cells undergoing epithelial-mesenchymal transition.
Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation.
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo.
VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR-PI3K-AKT pathway.
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
Andrographolide enhanced radiosensitivity by downregulating glycolysis via the inhibition of the PI3K-Akt-mTOR signaling pathway in HCT116 colorectal cancer cells.
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma.
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
The immunoregulatory protein B7-H3 promotes aerobic glycolysis in oral squamous carcinoma via PI3K/Akt/mTOR pathway.
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer.
High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
The effect of intervertebral disc degenerative change on biological characteristics of nucleus pulposus mesenchymal stem cell: an in vitro study in rats.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
MicroRNA-31-5p enhances the Warburg effect via targeting FIH.
A 3D human placenta-on-a-chip model to probe nanoparticle exposure at the placental barrier.
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma.
Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy.
Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21.
Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro.
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1.
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis.
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Resveratrol inhibits VEGF-induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation.
Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response.
Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments.
Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling.
Fructose-1,6-Bisphosphatase 1 Reduces 18F FDG Uptake in Hepatocellular Carcinoma.
Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro.
miR-210 protects renal cell against hypoxia-induced apoptosis by targeting HIF-1 alpha.
Maternal Choline Supplementation Modulates Placental Nutrient Transport and Metabolism in Late Gestation of Mouse Pregnancy.
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.
In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT.
MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells.
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma.
Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo.
Characterization of a near-infrared fluorescent DCPO-tagged glucose analogue for cancer cell imaging.
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors.
The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain.
Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice.
Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade.
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.
Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice.
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α.
20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.
Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging.
Zhang L, Yu X, Wu Y, Fu H, Xu P, Zheng Y, Wen L, Yang X, Zhang F, Hu M, Wang H, Liu X, Qiao J, Peng C, Gao R, Saffery R, Fu Y, Qi H, Tong C, Kilby MD, Baker PN
Frontiers in cell and developmental biology 2021;9:722024
Frontiers in cell and developmental biology 2021;9:722024
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Jin Y, Zhang M, Li M, Zhang H, Zhao L, Qian C, Li S, Zhang H, Gao M, Pan B, Li R, Wan X, Cao C
Frontiers in molecular biosciences 2021;8:725319
Frontiers in molecular biosciences 2021;8:725319
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury.
Ni S, Yang B, Xia L, Zhang H
Mediators of inflammation 2021;2021:5591582
Mediators of inflammation 2021;2021:5591582
LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis.
Yang L, Pei L, Yi J
Neuropsychiatric disease and treatment 2021;17:2027-2040
Neuropsychiatric disease and treatment 2021;17:2027-2040
Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence.
Qin X, Liu R, Akter F, Qin L, Xie Q, Li Y, Qiao H, Zhao W, Jian Z, Liu R, Wu S
Journal of Cancer 2021;12(7):2073-2082
Journal of Cancer 2021;12(7):2073-2082
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Up-Regulation of Glycogen Synthesis and Degradation Enzyme Level Maintained Myocardial Glycogen in Huddling Brandt's Voles Under Cool Environments.
Xu JH, Wang Z, Mou JJ, Wang CL, Huang WM, Xue HL, Wu M, Chen L, Xu LX
Frontiers in physiology 2021;12:593129
Frontiers in physiology 2021;12:593129
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Luo Q, Xian P, Wang T, Wu S, Sun T, Wang W, Wang B, Yang H, Yang Y, Wang H, Liu W, Long Q
Theranostics 2021;11(12):5986-6005
Theranostics 2021;11(12):5986-6005
Activated Pancreatic Stellate Cells Enhance the Warburg Effect to Cause the Malignant Development in Chronic Pancreatitis.
Tao Y, Shao F, Cai M, Liu Z, Peng Y, Huang Q, Meng F
Frontiers in oncology 2021;11:714598
Frontiers in oncology 2021;11:714598
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Dong Q, Li Q, Duan L, Yin H, Wang X, Liu Y, Wang B, Li K, Yao X, Yuan G, Pan Y
Frontiers in oncology 2021;11:652008
Frontiers in oncology 2021;11:652008
MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis.
Zhang D, He Z, Shen Y, Wang J, Liu T, Jiang J
Frontiers in oncology 2021;11:651535
Frontiers in oncology 2021;11:651535
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
Meng H, Shen M, Li J, Zhang R, Li X, Zhao L, Huang G, Liu J
European journal of pharmacology 2021 Sep 5;906:174280
European journal of pharmacology 2021 Sep 5;906:174280
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Zhao Z, Li G, Han Y, Li Y, Ji Z, Guo R, Yu X
Aging 2021 Sep 14;13(17):21122-21133
Aging 2021 Sep 14;13(17):21122-21133
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Li X, Zhang Y, Wang X, Lin F, Cheng X, Wang Z, Wang X
Cell biology and toxicology 2021 Sep 12;
Cell biology and toxicology 2021 Sep 12;
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis.
Wang Z, Chen L, Huang Y, Luo M, Wang H, Jiang Z, Zheng J, Yang Z, Chen Z, Zhang C, Long L, Wang Y, Li X, Liao F, Gan Y, Luo P, Liu Y, Wang Y, XuTan, Zhou Z, Zhang A, Shi C
Redox biology 2021 Oct;46:102082
Redox biology 2021 Oct;46:102082
Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase.
Figlak K, Williams G, Bertolini M, Paus R, Philpott MP
Scientific reports 2021 Oct 21;11(1):20761
Scientific reports 2021 Oct 21;11(1):20761
MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis.
Zhou K, Wei Y, Li X, Yang X
Life sciences 2021 Oct 1;282:119798
Life sciences 2021 Oct 1;282:119798
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.
He R, Wang Z, Cui M, Liu S, Wu W, Chen M, Wu Y, Qu Y, Lin H, Chen S, Wang B, Shao Z
Autophagy 2021 Nov;17(11):3338-3360
Autophagy 2021 Nov;17(11):3338-3360
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.
Yu B, Zhang F, Liu L, Liang Y, Tang X, Peng Y, Cai F, Zeng D, Yuan X, Li J, Guo Y, Lv B, Wang M, Liao Q, Lv XB
Biochemical and biophysical research communications 2021 May 21;554:25-32
Biochemical and biophysical research communications 2021 May 21;554:25-32
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
Microenvironment Analysis of Prognosis and Molecular Signature of Immune-Related Genes in Lung Adenocarcinoma.
Ling B, Huang Z, Huang S, Qian L, Li G, Tang Q
Oncology research 2021 Mar 16;28(6):561-578
Oncology research 2021 Mar 16;28(6):561-578
Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.
Shi W, Fu Y, Wang Y
Oncology letters 2021 Jul;22(1):527
Oncology letters 2021 Jul;22(1):527
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
Pei L, Le Y, Chen H, Feng J, Liu Z, Zhu J, Wang C, Chen L, Dou X, Lu D
Fitoterapia 2021 Jul;152:104922
Fitoterapia 2021 Jul;152:104922
RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
Hahm ER, Kim SH, Singh KB, Singh SV
Molecular carcinogenesis 2021 Jan;60(1):3-14
Molecular carcinogenesis 2021 Jan;60(1):3-14
Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia.
Wang YJ, Yang B, Lai Q, Shi JF, Peng JY, Zhang Y, Hu KS, Li YQ, Peng JW, Yang ZZ, Li YT, Pan Y, Koeffler HP, Liao JY, Yin D
RNA biology 2021 Jan;18(1):131-143
RNA biology 2021 Jan;18(1):131-143
Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.
Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, Huang M, Liu R, Lin Y, Tan C, Xu M, Zhang Z
Cell biology and toxicology 2021 Feb;37(1):35-49
Cell biology and toxicology 2021 Feb;37(1):35-49
Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway.
Sun LT, Zhang LY, Shan FY, Shen MH, Ruan SM
Chinese journal of natural medicines 2021 Feb;19(2):143-152
Chinese journal of natural medicines 2021 Feb;19(2):143-152
Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway.
Guo XH, Jiang SS, Zhang LL, Hu J, Edelbek D, Feng YQ, Yang ZX, Hu PC, Zhong H, Yang GH, Yang F
Oncology reports 2021 Dec;46(6)
Oncology reports 2021 Dec;46(6)
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222
International immunopharmacology 2021 Dec;101(Pt B):108222
Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues.
Xu Y, Shi T, Cui X, Yan L, Wang Q, Xu X, Zhao Q, Xu X, Tang QQ, Tang H, Pan D
The EMBO journal 2021 Dec 15;40(24):e108069
The EMBO journal 2021 Dec 15;40(24):e108069
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Glucose-Lipopeptide Conjugates Reveal the Role of Glucose Modification Position in Complexation and the Potential of Malignant Melanoma Therapy.
Zhao X, Zhang P, Li Y, Wu S, Li F, Wang Y, Liang S, He X, Zeng Y, Liu Z
Journal of medicinal chemistry 2021 Aug 12;64(15):11483-11495
Journal of medicinal chemistry 2021 Aug 12;64(15):11483-11495
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
Nakano D, Kawaguchi T, Iwamoto H, Hayakawa M, Koga H, Torimura T
PloS one 2020;15(4):e0232283
PloS one 2020;15(4):e0232283
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer.
Shen LF, Zhou SH, Guo Y
OncoTargets and therapy 2020;13:11221-11235
OncoTargets and therapy 2020;13:11221-11235
MiR-935/HIF1α Feedback Loop Inhibits the Proliferation and Invasiveness of Glioma.
Huang G, Chen J, Liu J, Zhang X, Duan H, Fang Q
OncoTargets and therapy 2020;13:10817-10828
OncoTargets and therapy 2020;13:10817-10828
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Hu Y, Deng K, Pan M, Liu S, Li W, Huang J, Yao J, Zuo J
American journal of translational research 2020;12(7):3842-3857
American journal of translational research 2020;12(7):3842-3857
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Chen L, Peng J, Wang Y, Jiang H, Wang W, Dai J, Tang M, Wei Y, Kuang H, Xu G, Xu H, Zhou F
American journal of translational research 2020;12(2):428-446
American journal of translational research 2020;12(2):428-446
HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway via relieving miR-451 inhibitory effect on CAB39 in lung cancer cells.
Wang HM, Lu YJ, He L, Gu NJ, Wang SY, Qiu XS, Wang EH, Wu GP
Therapeutic advances in chronic disease 2020;11:2040622320957143
Therapeutic advances in chronic disease 2020;11:2040622320957143
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
Long Noncoding RNA MIR210HG Promotes the Warburg Effect and Tumor Growth by Enhancing HIF-1α Translation in Triple-Negative Breast Cancer.
Du Y, Wei N, Ma R, Jiang SH, Song D
Frontiers in oncology 2020;10:580176
Frontiers in oncology 2020;10:580176
Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.
Wang F, Xie N, Zhou J, Dai M, Zhang Q, Hardiman PJ, Qu F
EBioMedicine 2020 Oct;60:102993
EBioMedicine 2020 Oct;60:102993
Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice.
Yang S, Zhou F, Ma M, Yuan Y, Zhao S, Yu P
Neurochemical research 2020 Oct;45(10):2474-2486
Neurochemical research 2020 Oct;45(10):2474-2486
Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model.
Wu L, Zheng Q, Guo YY, Zhang KN, Luo J, Xiao S, Li WJ, Yang M
Journal of ethnopharmacology 2020 Oct 5;260:112783
Journal of ethnopharmacology 2020 Oct 5;260:112783
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.
Gao Z, Dlamini MB, Ge H, Jiang L, Geng C, Li Q, Shi X, Liu Y, Cao J
Toxicology letters 2020 Oct 1;331:178-187
Toxicology letters 2020 Oct 1;331:178-187
Platelet-rich plasma improves chronic inflammatory pain by inhibiting PKM2-mediated aerobic glycolysis in astrocytes.
Wei X, Jin XH, Meng XW, Hua J, Ji FH, Wang LN, Yang JP
Annals of translational medicine 2020 Nov;8(21):1456
Annals of translational medicine 2020 Nov;8(21):1456
Vitamin K2 promotes PI3K/AKT/HIF-1α-mediated glycolysis that leads to AMPK-dependent autophagic cell death in bladder cancer cells.
Duan F, Mei C, Yang L, Zheng J, Lu H, Xia Y, Hsu S, Liang H, Hong L
Scientific reports 2020 May 7;10(1):7714
Scientific reports 2020 May 7;10(1):7714
The effect of high glucose on the biological characteristics of nucleus pulposus-derived mesenchymal stem cells.
Liu Y, Li Y, Nan LP, Wang F, Zhou SF, Wang JC, Feng XM, Zhang L
Cell biochemistry and function 2020 Mar;38(2):130-140
Cell biochemistry and function 2020 Mar;38(2):130-140
Immunohistochemistry and gene expression of GLUT1, RUNX2 and MTOR in reparative dentinogenesis.
Takeuchi R, Ohkura N, Yoshiba K, Tohma A, Yoshiba N, Edanami N, Shirakashi M, Belal RS, Ohshima H, Noiri Y
Oral diseases 2020 Mar;26(2):341-349
Oral diseases 2020 Mar;26(2):341-349
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.
Wu Z, Jia J, Xu X, Xu M, Peng G, Ma J, Jiang X, Yao J, Yao K, Li L, Tang H
PLoS pathogens 2020 Jun;16(6):e1008568
PLoS pathogens 2020 Jun;16(6):e1008568
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, Qiu B, Tang B
Oncology reports 2020 Jul;44(1):103-114
Oncology reports 2020 Jul;44(1):103-114
Decreased glucose bioavailability and elevated aspartate metabolism in prostate cancer cells undergoing epithelial-mesenchymal transition.
Chen Y, Wang K, Liu T, Chen J, Lv W, Yang W, Xu S, Wang X, Li L
Journal of cellular physiology 2020 Jul;235(7-8):5602-5612
Journal of cellular physiology 2020 Jul;235(7-8):5602-5612
Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation.
Yang D, Peng M, Hou Y, Qin Y, Wan X, Zhu P, Liu S, Yang L, Zeng H, Jin T, Qiu Y, Li Q, Liu M
Cell death & disease 2020 Jul 3;11(7):508
Cell death & disease 2020 Jul 3;11(7):508
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, Cao X, Zhou Y, Xie M, Shi Y, Zeng Y, Bu H
Carcinogenesis 2020 Jul 14;41(7):972-983
Carcinogenesis 2020 Jul 14;41(7):972-983
Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo.
Conroy LR, Dougherty S, Kruer T, Metcalf S, Lorkiewicz P, He L, Yin X, Zhang X, Arumugam S, Young LEA, Sun RC, Clem BF
Cancers 2020 Jan 17;12(1)
Cancers 2020 Jan 17;12(1)
VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR-PI3K-AKT pathway.
Zhangyuan G, Wang F, Zhang H, Jiang R, Tao X, Yu D, Jin K, Yu W, Liu Y, Yin Y, Shen J, Xu Q, Zhang W, Sun B
Oncogene 2020 Feb;39(6):1213-1230
Oncogene 2020 Feb;39(6):1213-1230
Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.
Shen Z, Zeng L, Zhang Z
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
Molecular therapy. Nucleic acids 2020 Dec 4;22:1016-1024
Andrographolide enhanced radiosensitivity by downregulating glycolysis via the inhibition of the PI3K-Akt-mTOR signaling pathway in HCT116 colorectal cancer cells.
Li X, Tian R, Liu L, Wang L, He D, Cao K, Ma JK, Huang C
The Journal of international medical research 2020 Aug;48(8):300060520946169
The Journal of international medical research 2020 Aug;48(8):300060520946169
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038
Biochemical pharmacology 2020 Aug;178:114038
Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells.
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, Sun L
Life sciences 2020 Aug 15;255:117846
Life sciences 2020 Aug 15;255:117846
Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.
Gillen AE, Riemondy KA, Amani V, Griesinger AM, Gilani A, Venkataraman S, Madhavan K, Prince E, Sanford B, Hankinson TC, Handler MH, Vibhakar R, Jones KL, Mitra S, Hesselberth JR, Foreman NK, Donson AM
Cell reports 2020 Aug 11;32(6):108023
Cell reports 2020 Aug 11;32(6):108023
MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line.
Zhang Q, Ma XF, Dong MZ, Tan J, Zhang J, Zhuang LK, Liu SS, Xin YN
Lipids in health and disease 2020 Apr 16;19(1):76
Lipids in health and disease 2020 Apr 16;19(1):76
Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma.
Chen R, Zhou X, Huang G, Liu J
Contrast media & molecular imaging 2019;2019:9463926
Contrast media & molecular imaging 2019;2019:9463926
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Yu W, Yang Z, Huang R, Min Z, Ye M
OncoTargets and therapy 2019;12:2861-2868
OncoTargets and therapy 2019;12:2861-2868
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines.
Chai Z, Yang Y, Gu Z, Cai X, Ye W, Kong L, Qiu X, Ying L, Wang Z, Wang L
OncoTargets and therapy 2019;12:10415-10425
OncoTargets and therapy 2019;12:10415-10425
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells.
Pan C, Liu Q, Wu X
Cancer management and research 2019;11:10145-10156
Cancer management and research 2019;11:10145-10156
The immunoregulatory protein B7-H3 promotes aerobic glycolysis in oral squamous carcinoma via PI3K/Akt/mTOR pathway.
Li Z, Liu J, Que L, Tang X
Journal of Cancer 2019;10(23):5770-5784
Journal of Cancer 2019;10(23):5770-5784
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Lu H, Cheng S, Wu C, Zheng S, Hong W, Liu L, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer.
Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, Xu W, Sun Q, Zhang Z, Ni Q, Yu X, Zhang B, Xu X
Cell proliferation 2019 May;52(3):e12603
Cell proliferation 2019 May;52(3):e12603
Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
Zhang W, Shao W, Dong Z, Zhang S, Liu C, Chen S
Cell death & disease 2019 May 28;10(6):404
Cell death & disease 2019 May 28;10(6):404
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, Huang Y, Zhu Y, Shen Y, Zhu Y, Dai B, Hu X, Ye D, Wang Z
Cancer research 2019 May 15;79(10):2604-2618
Cancer research 2019 May 15;79(10):2604-2618
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer.
Peng W, Huang W, Ge X, Xue L, Zhao W, Xue J
EBioMedicine 2019 Jun;44:375-386
EBioMedicine 2019 Jun;44:375-386
High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.
Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH
Cell metabolism 2019 Jun 4;29(6):1334-1349.e10
Cell metabolism 2019 Jun 4;29(6):1334-1349.e10
UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer.
Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, Zhang Z, Liu M, Ni Q, Yu X, Xu X
Cancer letters 2019 Jun 28;452:226-236
Cancer letters 2019 Jun 28;452:226-236
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
Liu L, Shi Y, Shi J, Wang H, Sheng Y, Jiang Q, Chen H, Li X, Dong J
Cell death & disease 2019 Jun 12;10(6):463
Cell death & disease 2019 Jun 12;10(6):463
The effect of intervertebral disc degenerative change on biological characteristics of nucleus pulposus mesenchymal stem cell: an in vitro study in rats.
Liu Y, Li Y, Huang ZN, Wang ZY, Nan LP, Wang F, Zhou SF, Wang JC, Feng XM, Zhang L
Connective tissue research 2019 Jul;60(4):376-388
Connective tissue research 2019 Jul;60(4):376-388
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
Huang X, Gan G, Wang X, Xu T, Xie W
Autophagy 2019 Jul;15(7):1258-1279
Autophagy 2019 Jul;15(7):1258-1279
MicroRNA-31-5p enhances the Warburg effect via targeting FIH.
Zhu B, Cao X, Zhang W, Pan G, Yi Q, Zhong W, Yan D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):545-556
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):545-556
A 3D human placenta-on-a-chip model to probe nanoparticle exposure at the placental barrier.
Yin F, Zhu Y, Zhang M, Yu H, Chen W, Qin J
Toxicology in vitro : an international journal published in association with BIBRA 2019 Feb;54:105-113
Toxicology in vitro : an international journal published in association with BIBRA 2019 Feb;54:105-113
Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells.
Chai XX, Le YF, Wang JC, Mei CX, Feng JF, Zhao H, Wang C, Lu DZ
Journal of food science 2019 Dec;84(12):3825-3832
Journal of food science 2019 Dec;84(12):3825-3832
Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.
Singh KB, Hahm ER, Alumkal JJ, Foley LM, Hitchens TK, Shiva SS, Parikh RA, Jacobs BL, Singh SV
Carcinogenesis 2019 Dec 31;40(12):1545-1556
Carcinogenesis 2019 Dec 31;40(12):1545-1556
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
Paul BT, Tesfay L, Winkler CR, Torti FM, Torti SV
Scientific reports 2019 Dec 23;9(1):19634
Scientific reports 2019 Dec 23;9(1):19634
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma.
Jiang E, Xu Z, Wang M, Yan T, Huang C, Zhou X, Liu Q, Wang L, Chen Y, Wang H, Liu K, Shao Z, Shang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5690-5703
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5690-5703
Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy.
Wang W, Cheng Y, Yu P, Wang H, Zhang Y, Xu H, Ye Q, Yuan A, Hu Y, Wu J
Nature communications 2019 Apr 5;10(1):1580
Nature communications 2019 Apr 5;10(1):1580
Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21.
Yan B, Cheng L, Jiang Z, Chen K, Zhou C, Sun L, Cao J, Qian W, Li J, Shan T, Lei J, Ma Q, Ma J
Oxidative medicine and cellular longevity 2018;2018:1346958
Oxidative medicine and cellular longevity 2018;2018:1346958
Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro.
Jiang T, Zhou ML, Fan J
OncoTargets and therapy 2018;11:7865-7872
OncoTargets and therapy 2018;11:7865-7872
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
Yang Y, Cao Y, Chen L, Liu F, Qi Z, Cheng X, Wang Z
Cancer medicine 2018 Sep;7(9):4610-4618
Cancer medicine 2018 Sep;7(9):4610-4618
miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1.
Santasusagna S, Moreno I, Navarro A, Muñoz C, Martinez F, Hernández R, Castellano JJ, Monzo M
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1161-1167
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1161-1167
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Zhang X, Li Y, Ma Y, Yang L, Wang T, Meng X, Zong Z, Sun X, Hua X, Li H
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer.
Fan L, Huang C, Li J, Gao T, Lin Z, Yao T
International journal of molecular medicine 2018 Oct;42(4):2247-2259
International journal of molecular medicine 2018 Oct;42(4):2247-2259
Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib.
Yao J, Man S, Dong H, Yang L, Ma L, Gao W
The Journal of steroid biochemistry and molecular biology 2018 Oct;183:159-166
The Journal of steroid biochemistry and molecular biology 2018 Oct;183:159-166
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis.
Li Q, Li Y, Liang L, Li J, Luo D, Liu Q, Cai S, Li X
Cell communication and signaling : CCS 2018 Jun 8;16(1):26
Cell communication and signaling : CCS 2018 Jun 8;16(1):26
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Wang S, Li J, Xie J, Liu F, Duan Y, Wu Y, Huang S, He X, Wang Z, Wu X
Oncogene 2018 Jul;37(30):4164-4180
Oncogene 2018 Jul;37(30):4164-4180
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Wu Q, Chen X, Wang J, Sun P, Weng M, Chen W, Sun Z, Zhu M, Miao C
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
Resveratrol inhibits VEGF-induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation.
Wu H, He L, Shi J, Hou X, Zhang H, Zhang X, An Q, Fan F
Clinical and experimental pharmacology & physiology 2018 Dec;45(12):1265-1273
Clinical and experimental pharmacology & physiology 2018 Dec;45(12):1265-1273
Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response.
Wang Y, Li Q, Liu F, Jin S, Zhang Y, Zhang T, Zhu Y, Zhou Y
International journal of oral science 2018 Aug 15;10(3):27
International journal of oral science 2018 Aug 15;10(3):27
Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments.
Brownlow ML, Jung SH, Moore RJ, Bechmann N, Jankord R
Frontiers in molecular neuroscience 2017;10:129
Frontiers in molecular neuroscience 2017;10:129
Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling.
Wei S, Fan Q, Yang L, Zhang X, Ma Y, Zong Z, Hua X, Su D, Sun H, Li H, Liu Z
Oncology reports 2017 Sep;38(3):1902-1908
Oncology reports 2017 Sep;38(3):1902-1908
Fructose-1,6-Bisphosphatase 1 Reduces 18F FDG Uptake in Hepatocellular Carcinoma.
Chen R, Li J, Zhou X, Liu J, Huang G
Radiology 2017 Sep;284(3):844-853
Radiology 2017 Sep;284(3):844-853
Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro.
Yao GD, Yang J, Li XX, Song XY, Hayashi T, Tashiro SI, Onodera S, Song SJ, Ikejima T
Acta pharmacologica Sinica 2017 Oct;38(10):1401-1411
Acta pharmacologica Sinica 2017 Oct;38(10):1401-1411
miR-210 protects renal cell against hypoxia-induced apoptosis by targeting HIF-1 alpha.
Liu LL, Li D, He YL, Zhou YZ, Gong SH, Wu LY, Zhao YQ, Huang X, Zhao T, Xu L, Wu KW, Li MG, Zhu LL, Fan M
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:258-271
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:258-271
Maternal Choline Supplementation Modulates Placental Nutrient Transport and Metabolism in Late Gestation of Mouse Pregnancy.
Kwan STC, King JH, Yan J, Wang Z, Jiang X, Hutzler JS, Klein HR, Brenna JT, Roberson MS, Caudill MA
The Journal of nutrition 2017 Nov;147(11):2083-2092
The Journal of nutrition 2017 Nov;147(11):2083-2092
A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism.
Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, Liang C, Meng Q, Xiang J, Liang D, Ji S, Liu J, Hu P, Liu L, Liu C, Long J, Ni Q, Yu X, Xu J
International journal of oncology 2017 May;50(5):1792-1800
International journal of oncology 2017 May;50(5):1792-1800
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, Li Z, Sun L, Wang L, He X, Wu G, Hu X, Wang L, Song L, Zhang H, Pan X, Li A, Gao P
EMBO reports 2017 May;18(5):809-825
EMBO reports 2017 May;18(5):809-825
HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.
Wu D, Huang RT, Hamanaka RB, Krause M, Oh MJ, Kuo CH, Nigdelioglu R, Meliton AY, Witt L, Dai G, Civelek M, Prabhakar NR, Fang Y, Mutlu GM
eLife 2017 May 30;6
eLife 2017 May 30;6
In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT.
Shen LF, Zhao X, Zhou SH, Lu ZJ, Zhao K, Fan J, Zhou ML
Oncotarget 2017 May 23;8(21):34709-34726
Oncotarget 2017 May 23;8(21):34709-34726
MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells.
Zhu W, Huang Y, Pan Q, Xiang P, Xie N, Yu H
Digestive diseases and sciences 2017 Mar;62(3):660-668
Digestive diseases and sciences 2017 Mar;62(3):660-668
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Cheng L, Jin Y, Liu M, Ruan M, Chen L
Oncotarget 2017 Mar 21;8(12):19843-19854
Oncotarget 2017 Mar 21;8(12):19843-19854
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, Liu J, Xiang J, Liang D, Hu Q, Ni Q, Yu X, Xu J
Cancer letters 2017 Mar 1;388:303-311
Cancer letters 2017 Mar 1;388:303-311
18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma.
Huang P, Zhao X, Xiao W, Dong Y, Hu G
Oncotarget 2017 Jun 13;8(24):39618-39626
Oncotarget 2017 Jun 13;8(24):39618-39626
Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Zhang XY, Sun ZK, Luo QY
Journal of molecular endocrinology 2017 Jan;58(1):15-23
Journal of molecular endocrinology 2017 Jan;58(1):15-23
Characterization of a near-infrared fluorescent DCPO-tagged glucose analogue for cancer cell imaging.
Fang Y, Zhang W, Zhu M, Chen S, Liu X, Lu W, Zhang X
Journal of photochemistry and photobiology. B, Biology 2017 Jan;166:264-271
Journal of photochemistry and photobiology. B, Biology 2017 Jan;166:264-271
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Cai X, Ding H, Liu Y, Pan G, Li Q, Yang Z, Liu W
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Li H, Li M, Pang Y, Liu F, Sheng D, Cheng X
Molecular medicine reports 2017 Dec;16(6):8563-8571
Molecular medicine reports 2017 Dec;16(6):8563-8571
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, Cheng R, Zhang Y, Zhang X, Chen H, Huang B, Cao Y
Oncotarget 2017 Dec 26;8(69):114328-114343
Oncotarget 2017 Dec 26;8(69):114328-114343
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
Wang S, Xie J, Li J, Liu F, Wu X, Wang Z
American journal of cancer research 2016;6(5):1108-17
American journal of cancer research 2016;6(5):1108-17
A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors.
Xu H, Li Z, Yu Y, Sizdahkhani S, Ho WS, Yin F, Wang L, Zhu G, Zhang M, Jiang L, Zhuang Z, Qin J
Scientific reports 2016 Nov 10;6:36670
Scientific reports 2016 Nov 10;6:36670
The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Wang J, Zhang P, Zhong J, Tan M, Ge J, Tao L, Li Y, Zhu Y, Wu L, Qiu J, Tong X
Oncotarget 2016 May 10;7(19):27142-57
Oncotarget 2016 May 10;7(19):27142-57
Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain.
Fang F, Gao Y, Wang T, Chen D, Liu J, Qian W, Cheng J, Gao R, Wang J, Xiao H
Toxicology letters 2016 Mar 14;245:59-67
Toxicology letters 2016 Mar 14;245:59-67
Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice.
Li J, Wang Y, Fang F, Chen D, Gao Y, Liu J, Gao R, Wang J, Xiao H
Environmental toxicology and pharmacology 2016 Apr;43:7-12
Environmental toxicology and pharmacology 2016 Apr;43:7-12
Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade.
Teng CF, Hsieh WC, Wu HC, Lin YJ, Tsai HW, Huang W, Su IJ
PloS one 2015;10(4):e0122373
PloS one 2015;10(4):e0122373
Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition.
Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, Wang B, Wang C, Shi D
Marine drugs 2015 Jul 17;13(7):4452-69
Marine drugs 2015 Jul 17;13(7):4452-69
Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice.
Fang F, Chen D, Yu P, Qian W, Zhou J, Liu J, Gao R, Wang J, Xiao H
General and comparative endocrinology 2015 Feb 1;212:44-50
General and comparative endocrinology 2015 Feb 1;212:44-50
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Huang, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P, Zhang H
Cell reports 2014 Sep 25;8(6):1930-1942
Cell reports 2014 Sep 25;8(6):1930-1942
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Ma X, Li C, Sun L, Huang D, Li T, He X, Wu G, Yang Z, Zhong X, Song L, Gao P, Zhang H
Nature communications 2014 Oct 10;5:5212
Nature communications 2014 Oct 10;5:5212
Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α.
Zhao W, Chang C, Cui Y, Zhao X, Yang J, Shen L, Zhou J, Hou Z, Zhang Z, Ye C, Hasenmayer D, Perkins R, Huang X, Yao X, Yu L, Huang R, Zhang D, Guo H, Yan J
The Journal of biological chemistry 2014 Apr 18;289(16):11219-11229
The Journal of biological chemistry 2014 Apr 18;289(16):11219-11229
20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.
Lai G, Wu J, Liu X, Zhao Y
Molecular endocrinology (Baltimore, Md.) 2012 Nov;26(11):1907-16
Molecular endocrinology (Baltimore, Md.) 2012 Nov;26(11):1907-16
Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging.
Vendrell M, Samanta A, Yun SW, Chang YT
Organic & biomolecular chemistry 2011 Jul 7;9(13):4760-2
Organic & biomolecular chemistry 2011 Jul 7;9(13):4760-2
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 21829-1-AP(SLC2A1,GLUT1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SLC2A1 antibody 21829-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21829-1-AP(SLC2A1,GLUT1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21829-1-AP(SLC2A1,GLUT1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLUT1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GLUT1. This antibody recognizes human,mouse,rat antigen. The GLUT1 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.