NB300-666

Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, Kerkelä R, Myllyharju J, Dimova EY, Serpi R, Koivunen P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5590-5609

Mammalian embryos show metabolic plasticity toward the surrounding environment during neural tube closure.

Miyazawa H, Yamamoto M, Yamaguchi Y, Miura M
Genes to cells : devoted to molecular & cellular mechanisms 2018 Sep;23(9):794-802

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia.

Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J
Cell reports 2018 Oct 16;25(3):561-570.e6

Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6.

Finicle BT, Ramirez MU, Liu G, Selwan EM, McCracken AN, Yu J, Joo Y, Nguyen J, Ou K, Roy SG, Mendoza VD, Corrales DV, Edinger AL
Journal of cell science 2018 Jun 25;131(12)

Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.

Kim SM, Roy SG, Chen B, Nguyen TM, McMonigle RJ, McCracken AN, Zhang Y, Kofuji S, Hou J, Selwan E, Finicle BT, Nguyen TT, Ravi A, Ramirez MU, Wiher T, Guenther GG, Kono M, Sasaki AT, Weisman LS, Potma EO, Tromberg BJ, Edwards RA, Hanessian S, Edinger AL
The Journal of clinical investigation 2016 Nov 1;126(11):4088-4102

Reck enables cerebrovascular development by promoting canonical Wnt signaling.

Ulrich F, Carretero-Ortega J, Menéndez J, Narvaez C, Sun B, Lancaster E, Pershad V, Trzaska S, Véliz E, Kamei M, Prendergast A, Kidd KR, Shaw KM, Castranova DA, Pham VN, Lo BD, Martin BL, Raible DW, Weinstein BM, Torres-Vázquez J
Development (Cambridge, England) 2016 Jan 1;143(1):147-59

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.

Joyal JS, Sun Y, Gantner ML, Shao Z, Evans LP, Saba N, Fredrick T, Burnim S, Kim JS, Patel G, Juan AM, Hurst CG, Hatton CJ, Cui Z, Pierce KA, Bherer P, Aguilar E, Powner MB, Vevis K, Boisvert M, Fu Z, Levy E, Fruttiger M, Packard A, Rezende FA, Maranda B, Sapieha P, Chen J, Friedlander M, Clish CB, Smith LE
Nature medicine 2016 Apr;22(4):439-45

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis.

Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N, Nathans J, Stainier DY
eLife 2015 Jun 8;4

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.

Lin AP, Abbas S, Kim SW, Ortega M, Bouamar H, Escobedo Y, Varadarajan P, Qin Y, Sudderth J, Schulz E, Deutsch A, Mohan S, Ulz P, Neumeister P, Rakheja D, Gao X, Hinck A, Weintraub ST, DeBerardinis RJ, Sill H, Dahia PL, Aguiar RC
Nature communications 2015 Jul 16;6:7768

The contributions of HIF-target genes to tumor growth in RCC.

Zhang T, Niu X, Liao L, Cho EA, Yang H
PloS one 2013;8(11):e80544

Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.

Couch JA, Yu YJ, Zhang Y, Tarrant JM, Fuji RN, Meilandt WJ, Solanoy H, Tong RK, Hoyte K, Luk W, Lu Y, Gadkar K, Prabhu S, Ordonia BA, Nguyen Q, Lin Y, Lin Z, Balazs M, Scearce-Levie K, Ernst JA, Dennis MS, Watts RJ
Science translational medicine 2013 May 1;5(183):183ra57, 1-12

A cell-penetrating peptide suppresses the hypoxia inducible factor-1 function by binding to the helix-loop-helix domain of the aryl hydrocarbon receptor nuclear translocator.

Wang Y, Thompson JD, Chan WK
Chemico-biological interactions 2013 Apr 25;203(2):401-11

Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C.

Kuzmanov A, Wielockx B, Rezaei M, Kettelhake A, Breier G
International journal of cancer 2012 Sep 1;131(5):E603-13

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q, Yang H
Oncogene 2012 Feb 9;31(6):776-86

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Koivunen P, Lee S, Duncan CG, Lopez G, Lu G, Ramkissoon S, Losman JA, Joensuu P, Bergmann U, Gross S, Travins J, Weiss S, Looper R, Ligon KL, Verhaak RG, Yan H, Kaelin WG Jr
Nature 2012 Feb 15;483(7390):484-8

The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

Zhou L, Yang H
PloS one 2011;6(9):e23936

The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

X Niu, T Zhang, L Liao, L Zhou, D J Lindner, M Zhou, B Rini, Q Yan, H Yang
Oncogene 2011 Jul;():-

Regulation of TFEB and V-ATPases by mTORC1.

Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J
The EMBO journal 2011 Jul 29;30(16):3242-58

Human cytomegalovirus activates glucose transporter 4 expression to increase glucose uptake during infection.

Yu Y, Maguire TG, Alwine JC
Journal of virology 2011 Feb;85(4):1573-80

Molecular characterization of antibody epitopes of Ehrlichia chaffeensis ankyrin protein 200 and tandem repeat protein 47 and evaluation of synthetic immunodeterminants for serodiagnosis of human monocytotropic ehrlichiosis.

Luo T, Zhang X, Nicholson WL, Zhu B, McBride JW
Clinical and vaccine immunology : CVI 2010 Jan;17(1):87-97

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.

Hyvärinen J, Hassinen IE, Sormunen R, Mäki JM, Kivirikko KI, Koivunen P, Myllyharju J
The Journal of biological chemistry 2010 Apr 30;285(18):13646-57

A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.

Minamishima YA, Moslehi J, Padera RF, Bronson RT, Liao R, Kaelin WG Jr
Molecular and cellular biology 2009 Nov;29(21):5729-41

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.

Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG Jr
Blood 2008 Mar 15;111(6):3236-44

Previous or ongoing schistosome infections do not compromise the efficacy of the attenuated cercaria vaccine.

Kariuki TM, Van Dam GJ, Deelder AM, Farah IO, Yole DS, Wilson RA, Coulson PS
Infection and immunity 2006 Jul;74(7):3979-86

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Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: Glut1 Antibody [NB300-666] - WB analysis of purified Glucose Transporter (GLUT1) with GLUT1 antibody at a dilution of 1:2000.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: Glut1 Antibody [NB300-666] - Rat brain cortical extracts (10 ug total protein per lane) on 10% SDS-PAGE gel. Antibody diluted 1:2000.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: Glut1 Antibody [NB300-666] - Western blot analysis of 786-mock cells stably expressing shRNA constructs. For HIF2A (NB100-480) and HIF1B (NB100-124) analysis, nuclear extracts were generated and analyzed. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0023936) licensed under a CC-BY licence. Glut-1 was detected using NB300-666 in whole cell extracts.