CABT-B11071

antibody from Creative Diagnostics

Targeting: PRELP prolargin, SLRR2A

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B11071

Provider

Creative Diagnostics

Product name

Mouse anti-Human PRELP monoclonal antibody, clone 4I2

Antibody type

Monoclonal

Description

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgM

Antibody clone number

4I2

Vial size

200 _l

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.