abx032926

antibody from Abbexa

Targeting: PRELP prolargin, SLRR2A

No application information provided.

Antibody Data

Product number

abx032926

Provider

Abbexa

Product name

Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) Antibody

Antibody type

Polyclonal

Description

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.