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antibody from antibodies-online
Targeting: SIRPA
BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500722 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- SIRP alpha antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human SIRP alpha 1. .Remarks: The sequences of the immunogenic peptide differ from those of Mouse, Rat and Bovine by one amino acid.
- Description
- DEAE Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Cloning of two members of the SIRP alpha family of protein tyrosine phosphatase binding proteins in cattle that are expressed on monocytes and a subpopulation of dendritic cells and which mediate binding to CD4 T cells.
A family of proteins that inhibit signalling through tyrosine kinase receptors.
Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.
A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.
Brooke GP, Parsons KR, Howard CJ
European journal of immunology 1998 Jan;28(1):1-11
European journal of immunology 1998 Jan;28(1):1-11
A family of proteins that inhibit signalling through tyrosine kinase receptors.
Kharitonenkov A, Chen Z, Sures I, Wang H, Schilling J, Ullrich A
Nature 1997 Mar 13;386(6621):181-6
Nature 1997 Mar 13;386(6621):181-6
Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.
Yamao T, Matozaki T, Amano K, Matsuda Y, Takahashi N, Ochi F, Fujioka Y, Kasuga M
Biochemical and biophysical research communications 1997 Feb 3;231(1):61-7
Biochemical and biophysical research communications 1997 Feb 3;231(1):61-7
A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.
Fujioka Y, Matozaki T, Noguchi T, Iwamatsu A, Yamao T, Takahashi N, Tsuda M, Takada T, Kasuga M
Molecular and cellular biology 1996 Dec;16(12):6887-99
Molecular and cellular biology 1996 Dec;16(12):6887-99
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SIRP alpha in THP-1 whole cell lysate with AP30784PU-N at 0.5 μg/ml dilution.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of SIRP alpha in THP-1 cells with AP30784PU-N at 1 ?g/ml.
