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antibody from Bioworld Technology, Inc
Targeting: SIRPA
BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Western blot [1]
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- Product number
- BS1324 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1324, RRID:AB_1663461
- Product name
- SIRP Ï«1 (R479) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 450-500 of Human SIRP-Ï«1.
- Description
- SIRP-Ï«1 is a substrate for activated receptor tyrosine kinases. In its tyrosine phosphorylated form, SIRP-Ï«1 binds to SH-PTP2 through SH2 interactions and acts as an SH-PTP2 substrate. SIRP-Ï«1 has been shown to have negative regulatory effects on cellular responses induced by growth factors, oncogenes and insulin. SIRP-ÉÇ1 shares extensive sequence homology with SIRP-Ï«1 in its extracellular portion but lacks the cytoplasmic portion. SIRP-ÎÛ, originally designated SIRP-ÉÇ2 (SIRP-B2, CD172g) has unique characteristics from both the Ï« and ÉÇ versions.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of SIRP-¦Á1 (R479) pAb at 1:500 dilutionLane1:Hela whole cell lysateLane2:Raw264.7 whole cell lysateLane3:sp2/0 whole cell lysate
