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LearnHPA001075
antibody from Atlas Antibodies
Targeting: TAF1
BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250
Immunocytochemistry
Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA001075 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001075, RRID:AB_1080179
- Product name
- Anti-TAF1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TAF1, Gene description: TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa, Alternative Gene Names: BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250, Validated applications: ChIP, ICC, IHC, Uniprot ID: P21675, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing
Pathogenic SREK1 decrease in Huntington’s disease lowers TAF1 mimicking X-linked dystonia parkinsonism
Tshilenge K, Bons J, Aguirre C, Geronimo-Olvera C, Shah S, Rose J, Gerencser A, Mak S, Ehrlich M, Bragg D, Schilling B, Ellerby L
Neurobiology of Disease 2024;190
Neurobiology of Disease 2024;190
Pathogenic SREK1 decrease in Huntington’s disease lowers TAF1 mimicking X-linked dystonia parkinsonism
Lucas J, Pintado B, Pérez-Álvarez M, García-Escudero R, Domínguez V, Sánchez-Martín M, Santos-Galindo M, Cabrera J, Hernández I
Brain 2020;143(7):2207-2219
Brain 2020;143(7):2207-2219
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-TAF1 (HPA001075, Lot 000011962) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
