AMM02592G

antibody from Leading Biology

Targeting: VAMP1 SYB1, VAMP-1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM02592G

Provider

Leading Biology

Product name

Synaptobrevin (VAMP) Antibody

Antibody type

Monoclonal

Description

Synaptobrevin (aka VAMP) is an integral membrane protein ofsynaptic vesicles that plays a major role in the formation of larger SNARE complexes, alongwith SNAP-25 and syntaxin. Synaptobrevin hasbeen shown to be essential for two fastsynapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter releaseand fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004).Decreased levels of synaptobrevin in human hippocampus and cortex have been correlatedwith cognitive defects in Alzheimer’s disease (Sze et al., 2000)

Reactivity

Human, Mouse, Rat, Bovine, Hamster, Porcine, Rabbit

Host

Mouse

Isotype

IgM

Antibody clone number

SP10

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.