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Protein structure
PTPN14
Protein tyrosine phosphatase non-receptor type 14PEZ
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-31871 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
OA
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| antibodies-online | ABIN4880983 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP2-61809 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 18053-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| R&D Systems | MAB4458 |
4 references | Monoclonal |
WB
IHC
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