CABT-B9235

antibody from Creative Diagnostics

Targeting: ENAH FLJ10773, MENA, NDPP1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B9235

Provider

Creative Diagnostics

Product name

Mouse anti-Mouse Mena monoclonal antibody, clone 32/Nfob

Antibody type

Monoclonal

Description

Abl and Disabled (Dab) are essential for correct axonal connections during Drosophila development. Mutations in Enabled (Ena) rescue the genetic defects caused by mutated Abl and Dab. Mena (Mammalian Ena) is a protein with significant homology to Eva, VASP, and WASP proteins. The murine Mena gene predicts a protein of 541 amino acids. However, two additional exons that could introduce 246 amino acids onto the C-terminal region have been identified. Homology searches identified two EVH domains (Ena-Vasp homology), one near each terminus of Mena. Antibodies to Mena detect 80 kDa, 88 kDa, and 140 kDa protein with the 80 kDa and 88 kDa proteins being widely expressed and the 140 kDa protein reportedly mainly found in brain tissue. Like VASP, Mena is localized to focal contacts and, when ectopically expressed, induces the formation of F-actin outgrowths in fibroblasts.

Reactivity

Human, Mouse, Rat, Chicken/Avian

Host

Mouse

Conjugate

Unconjugated

Isotype

IgA

Antibody clone number

32/Nfob

Vial size

50ug, 150ug

Concentration

250 Ã×g/ml

Storage

Store undiluted at -20°C.