BS6593

antibody from Bioworld Technology, Inc
Targeting: EPHX1 EPHX
Provider product page for BS6593
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6593 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EPHX1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human EPHX1.
Description
Epoxide hydrolases (EHs) are biotransformation enzymes that catalyze the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. The enzymatic hydration is essentially irreversible and produces mainly metabolites of lower reactivity that can be conjugated and excreted, and, therefore, are generally regarded as detoxifying. Microsomal EH (mEH) is one of many enzymes involved in the metabolism of endogenous levels of and exogenous toxicants such as tobacco-derived carcinogens. mEH exhibits a broad substrate specificity, while the soluble EH (sEH) is an enzyme with a "complementary" substrate specificity to mEH. The mEH protein is encoded by the EPHX1 gene, which maps to chromosome 1q42.12. Polymorphism of the EPHX1 gene is a risk factor ovarian cancer and hepatocellular carcinoma.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EPHX1 protein structure - BS6593 shown in red.