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- References [7]
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- Product number
- 12816-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12816-1-AP, RRID:AB_2129846
- Product name
- ITPKB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ITPKB antibody (Cat. #12816-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis.
Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.
Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca(2+) mobilization and the inflammatory activity of dendritic cells.
Severe combined immunodeficiency caused by inositol-trisphosphate 3-kinase B (ITPKB) deficiency.
miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.
Yan Y, Zhou S, Chen X, Yi Q, Feng S, Zhao Z, Liu Y, Liang Q, Xu Z, Li Z, Sun L
Signal transduction and targeted therapy 2024 Mar 4;9(1):58
Signal transduction and targeted therapy 2024 Mar 4;9(1):58
Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.
Ohene-Nyako M, Nass SR, Richard HT, Lukande R, Nicol MR, McRae M, Knapp PE, Hauser KF
ASN neuro 2023 Jan-Dec;15:17590914231158218
ASN neuro 2023 Jan-Dec;15:17590914231158218
Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status.
Di Leva F, Filosi M, Oyston L, Silvestri E, Picard A, Lavdas AA, Lobbestael E, Baekelandt V, Neely GG, Pramstaller PP, Hicks AA, Corti C
International journal of molecular sciences 2023 Jan 19;24(3)
International journal of molecular sciences 2023 Jan 19;24(3)
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Mo X, Niu Q, Ivanov AA, Tsang YH, Tang C, Shu C, Li Q, Qian K, Wahafu A, Doyle SP, Cicka D, Yang X, Fan D, Reyna MA, Cooper LAD, Moreno CS, Zhou W, Owonikoko TK, Lonial S, Khuri FR, Du Y, Ramalingam SS, Mills GB, Fu H
Cell 2022 May 26;185(11):1974-1985.e12
Cell 2022 May 26;185(11):1974-1985.e12
Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca(2+) mobilization and the inflammatory activity of dendritic cells.
Marongiu L, Mingozzi F, Cigni C, Marzi R, Di Gioia M, Garrè M, Parazzoli D, Sironi L, Collini M, Sakaguchi R, Morii T, Crosti M, Moro M, Schurmans S, Catelani T, Rotem R, Colombo M, Shears S, Prosperi D, Zanoni I, Granucci F
Science signaling 2021 Mar 30;14(676)
Science signaling 2021 Mar 30;14(676)
Severe combined immunodeficiency caused by inositol-trisphosphate 3-kinase B (ITPKB) deficiency.
Almutairi A, Wallace JG, Jaber F, Alosaimi MF, Jones J, Sallam MTH, Elnagdy MH, Chou J, Sobh A, Geha RS
The Journal of allergy and clinical immunology 2020 Jun;145(6):1696-1699.e6
The Journal of allergy and clinical immunology 2020 Jun;145(6):1696-1699.e6
miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.
Salta E, Sierksma A, Vanden Eynden E, De Strooper B
EMBO molecular medicine 2016 Sep;8(9):1005-18
EMBO molecular medicine 2016 Sep;8(9):1005-18
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ITPKB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ITPKB. This antibody recognizes human, mouse, rat antigen. The ITPKB antibody has been validated for the following applications: ELISA, WB analysis.
