Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16253-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16253-1-AP, RRID:AB_2278140
- Product name
- EXO1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXO1 antibody (Cat. #16253-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Telomeric Double Strand Breaks in G1 Human Cells Facilitate Formation of 5' C-Rich Overhangs and Recruitment of TERRA.
Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations.
DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
PCNA promotes processive DNA end resection by Exo1.
Nelson CB, Alturki TM, Luxton JJ, Taylor LE, Maranon DG, Muraki K, Murnane JP, Bailey SM
Frontiers in genetics 2021;12:644803
Frontiers in genetics 2021;12:644803
Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations.
Shen B, Chapman JH, Custance MF, Tricola GM, Jones CE, Furano AV
eLife 2020 Jan 6;9
eLife 2020 Jan 6;9
DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
Tammaro M, Liao S, Beeharry N, Yan H
Nucleic acids research 2016 Jan 8;44(1):221-31
Nucleic acids research 2016 Jan 8;44(1):221-31
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA
PLoS genetics 2015 Dec;11(12):e1005675
PLoS genetics 2015 Dec;11(12):e1005675
PCNA promotes processive DNA end resection by Exo1.
Chen X, Paudyal SC, Chin RI, You Z
Nucleic acids research 2013 Nov;41(20):9325-38
Nucleic acids research 2013 Nov;41(20):9325-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The EXO1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EXO1. This antibody recognizes human antigen. The EXO1 antibody has been validated for the following applications: ELISA, WB analysis.