Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN2849543 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-LC3 (APG8C) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Antibody clone number
- RB7613
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma.
Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK).
A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death.
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
Autophagy: dual roles in life and death?
Autophagy in metazoans: cell survival in the land of plenty.
Autophagy in health and disease: a double-edged sword.
LC3 conjugation system in mammalian autophagy.
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B.
Liu H, He Z, von Rütte T, Yousefi S, Hunger RE, Simon HU
Science translational medicine 2013 Sep 11;5(202):202ra123
Science translational medicine 2013 Sep 11;5(202):202ra123
Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK).
Thyagarajan A, Jedinak A, Nguyen H, Terry C, Baldridge LA, Jiang J, Sliva D
Nutrition and cancer 2010;62(5):630-40
Nutrition and cancer 2010;62(5):630-40
A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death.
Choi KC, Kim SH, Ha JY, Kim ST, Son JH
Journal of neurochemistry 2010 Jan;112(2):366-76
Journal of neurochemistry 2010 Jan;112(2):366-76
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
Liao G, Cheung S, Galeano J, Ji AX, Qin Q, Bi X
Brain research 2009 May 13;1270:140-51
Brain research 2009 May 13;1270:140-51
Autophagy: dual roles in life and death?
Baehrecke EH
Nature reviews. Molecular cell biology 2005 Jun;6(6):505-10
Nature reviews. Molecular cell biology 2005 Jun;6(6):505-10
Autophagy in metazoans: cell survival in the land of plenty.
Lum JJ, DeBerardinis RJ, Thompson CB
Nature reviews. Molecular cell biology 2005 Jun;6(6):439-48
Nature reviews. Molecular cell biology 2005 Jun;6(6):439-48
Autophagy in health and disease: a double-edged sword.
Shintani T, Klionsky DJ
Science (New York, N.Y.) 2004 Nov 5;306(5698):990-5
Science (New York, N.Y.) 2004 Nov 5;306(5698):990-5
LC3 conjugation system in mammalian autophagy.
Tanida I, Ueno T, Kominami E
The international journal of biochemistry & cell biology 2004 Dec;36(12):2503-18
The international journal of biochemistry & cell biology 2004 Dec;36(12):2503-18
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B.
He H, Dang Y, Dai F, Guo Z, Wu J, She X, Pei Y, Chen Y, Ling W, Wu C, Zhao S, Liu JO, Yu L
The Journal of biological chemistry 2003 Aug 1;278(31):29278-87
The Journal of biological chemistry 2003 Aug 1;278(31):29278-87
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC