Tissue expression
Cell line expression
Protein structure
CEP170
Centrosomal protein 170FAM68A, KAB, KIAA0470
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Invitrogen Antibodies | 41-3200 | 12 references | Monoclonal |
WB
ICC
IP
OA |
|
Novus Biologicals | NB100-55317 | 1 references | Polyclonal |
WB
ICC
IP
ChIP |
|
antibodies-online | ABIN188627 | 1 references | Polyclonal |
WB
ICC
IP
|
|
Proteintech Group | 18899-1-AP | 2 references | Polyclonal |
WB
EL
ICC
|
|
LSBio | LS-C198793 | Polyclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider