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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN350718 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350718, RRID:AB_10782797
- Product name
- anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the c-terminal of mouse AKT1 (RAC-alpha serine/threonine-protein kinase, PKB, RAC) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, human and chicken.
- Description
- Purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M
Cell 2006 Nov 3;127(3):635-48
Cell 2006 Nov 3;127(3):635-48
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
Anai M, Shojima N, Katagiri H, Ogihara T, Sakoda H, Onishi Y, Ono H, Fujishiro M, Fukushima Y, Horike N, Viana A, Kikuchi M, Noguchi N, Takahashi S, Takata K, Oka Y, Uchijima Y, Kurihara H, Asano T
The Journal of biological chemistry 2005 May 6;280(18):18525-35
The Journal of biological chemistry 2005 May 6;280(18):18525-35
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.
Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA
Science (New York, N.Y.) 2001 Oct 12;294(5541):374-80
Science (New York, N.Y.) 2001 Oct 12;294(5541):374-80
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.
Pekarsky Y, Koval A, Hallas C, Bichi R, Tresini M, Malstrom S, Russo G, Tsichlis P, Croce CM
Proceedings of the National Academy of Sciences of the United States of America 2000 Mar 28;97(7):3028-33
Proceedings of the National Academy of Sciences of the United States of America 2000 Mar 28;97(7):3028-33
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.
Cong LN, Chen H, Li Y, Zhou L, McGibbon MA, Taylor SI, Quon MJ
Molecular endocrinology (Baltimore, Md.) 1997 Dec;11(13):1881-90
Molecular endocrinology (Baltimore, Md.) 1997 Dec;11(13):1881-90
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