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LearnPAB2469
antibody from Abnova Corporation
Targeting: APOBEC3G
bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2469 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2469, RRID:AB_1571268
- Product name
- APOBEC3G polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human APOBEC3G.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 400 µl
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Stopak K, de Noronha C, Yonemoto W, Greene WC
Molecular cell 2003 Sep;12(3):591-601
Molecular cell 2003 Sep;12(3):591-601
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.
Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K
Journal of virology 2003 Nov;77(21):11398-407
Journal of virology 2003 Nov;77(21):11398-407
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D
Nature 2003 Jul 3;424(6944):99-103
Nature 2003 Jul 3;424(6944):99-103
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The APOBEC3G polyclonal antibody (Cat # PAB2469) is used in Western blot to detect APOBEC3G in HL-60 cell lysate.
- Validation comment
- Western Blot (Cell lysate)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the APOBEC3G polyclonal antibody (Cat # PAB2469) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
