Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS1298 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1298, RRID:AB_1663423
- Product name
- Presenilin 1 (S28) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids N-terminus of Human Presenilin 1.
- Description
- A novel protein, designated Presenilin 1 (also designated S182) and mapping to the AD3 locus of chromosome 14q24.3, has been described. Mutations in the gene encoding Presenilin 1 have been found in families suffering from early-onset Alzheimer£ªs disease. A highly related protein, designated Presenilin 2 (also designated STM2), shares 80% amino acid sequence identity with Presenilin 1. Presenilin 1 and Presenilin 2 have similar structures and represent novel members of the seven-pass transmembrane receptor superfamily.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Presenilin 1 (S28) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Mouse brain tissue lysateLane3:PC12 whole cell lysate