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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB12993 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12993, RRID:AB_10555913
- Product name
- PSEN1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Journal of neuroscience research 2004 Aug 1;77(3):309-22
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Selkoe DJ
Trends in cell biology 1998 Nov;8(11):447-53
Trends in cell biology 1998 Nov;8(11):447-53
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH
Nature 1995 Jun 29;375(6534):754-60
Nature 1995 Jun 29;375(6534):754-60
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of PSEN1 in human brain lysate with PSEN1 polyclonal antibody (Cat # PAB12993) at (A) 0.5, (B) 1, and (C) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of PSEN1 in human brain tissue with PSEN1 polyclonal antibody (Cat # PAB12993) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
