BS6665

antibody from Bioworld Technology, Inc
Targeting: MIF GIF, GLIF
Provider product page for BS6665
Western blot
Immunohistochemistry

Antibody data

Product number
BS6665 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MIF polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MIF.
Description
Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor Ï« (TNFÏ«), interleukin-1 (IL-1) and interferon-ÎÛ (IFN-ÎÛ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MIF protein structure - BS6665 shown in red.