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- Antibody Data
- Antigen structure
- References [19]
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- Product number
- 20118-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20118-1-AP, RRID:AB_10693531
- Product name
- SOX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SOX2 antibody (Cat. #20118-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Generation of homozygous and heterozygous REEP1 knockout induced pluripotent stem cell lines by CRISPR/Cas9 gene editing.
FPR3 reprograms glycolytic metabolism and stemness in gastric cancer via calcium-NFATc1 pathway.
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.
Patients' Stem Cells Differentiation in a 3D Environment as a Promising Experimental Tool for the Study of Amyotrophic Lateral Sclerosis.
Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM).
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer.
p57 Suppresses the Pluripotency and Proliferation of Mouse Embryonic Stem Cells by Positively Regulating p53 Activation.
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2.
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Early expression of Tubulin Beta-III in avian cranial neural crest cells.
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells.
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells.
Epigenetic reprogramming of human lung cancer cells with the extract of bovine parthenogenetic oocytes.
Korneck M, Leonhardt A, Schöls L, Hauser S
Stem cell research 2024 Jun;77:103378
Stem cell research 2024 Jun;77:103378
FPR3 reprograms glycolytic metabolism and stemness in gastric cancer via calcium-NFATc1 pathway.
Wang L, Mao X, Yu X, Su J, Li Z, Chen Z, Ren Y, Huang H, Wang W, Zhao C, Hu Y
Cancer letters 2024 Jul 1;593:216841
Cancer letters 2024 Jul 1;593:216841
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Bu J, Zhang Y, Wu S, Li H, Sun L, Liu Y, Zhu X, Qiao X, Ma Q, Liu C, Niu N, Xue J, Chen G, Yang Y, Liu C
Nature communications 2023 May 5;14(1):2602
Nature communications 2023 May 5;14(1):2602
Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.
Fukawa M, Shirai R, Torii T, Nakata K, Fukatsu S, Sato T, Homma K, Miyamoto Y, Yamauchi J
Biochemical and biophysical research communications 2023 Jul 5;664:50-58
Biochemical and biophysical research communications 2023 Jul 5;664:50-58
Patients' Stem Cells Differentiation in a 3D Environment as a Promising Experimental Tool for the Study of Amyotrophic Lateral Sclerosis.
Scarian E, Bordoni M, Fantini V, Jacchetti E, Raimondi MT, Diamanti L, Carelli S, Cereda C, Pansarasa O
International journal of molecular sciences 2022 May 11;23(10)
International journal of molecular sciences 2022 May 11;23(10)
Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM).
Laporte MH, Klena N, Hamel V, Guichard P
Nature methods 2022 Feb;19(2):216-222
Nature methods 2022 Feb;19(2):216-222
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer.
Zhang J, Lv X, Wei B, Gong X, Chen L
Cellular signalling 2022 Dec;100:110464
Cellular signalling 2022 Dec;100:110464
p57 Suppresses the Pluripotency and Proliferation of Mouse Embryonic Stem Cells by Positively Regulating p53 Activation.
Li N, Du Z, Li Y, Xu W, Yang Y, Peng H, Song T, Qin Q, Lei H, Hua J
Stem cells international 2021;2021:4968649
Stem cells international 2021;2021:4968649
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1.
Liu H, Qin H, Zhou Y, Yuan Y, Liu Y, Chen Y, Yang Y, Ni H, Xi T, Zheng L
Molecular carcinogenesis 2021 Jun;60(6):413-426
Molecular carcinogenesis 2021 Jun;60(6):413-426
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2.
Chang X, Zhang H, Yang Q, Pang L
Cell cycle (Georgetown, Tex.) 2020 Jun;19(11):1391-1403
Cell cycle (Georgetown, Tex.) 2020 Jun;19(11):1391-1403
Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
Liu YQ, Wang SK, Xu QQ, Yuan HQ, Guo YX, Wang Q, Kong F, Lin ZM, Sun DQ, Wang RM, Lou HX
Acta pharmacologica Sinica 2019 May;40(5):689-698
Acta pharmacologica Sinica 2019 May;40(5):689-698
Early expression of Tubulin Beta-III in avian cranial neural crest cells.
Chacon J, Rogers CD
Gene expression patterns : GEP 2019 Dec;34:119067
Gene expression patterns : GEP 2019 Dec;34:119067
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Zhang L, Yan Y, Jiang Y, Qian J, Jiang L, Hu G, Lu Y, Luo C
Oncology letters 2017 Oct;14(4):4263-4269
Oncology letters 2017 Oct;14(4):4263-4269
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Gao Y, Zhang Z, Li K, Gong L, Yang Q, Huang X, Hong C, Ding M, Yang H
Cell death & disease 2017 Jul 13;8(7):e2924
Cell death & disease 2017 Jul 13;8(7):e2924
Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells.
Liu Y, Lu R, Gu J, Chen Y, Zhang X, Zhang L, Wu H, Hua W, Zeng J
Environmental toxicology and pharmacology 2016 Jul;45:241-50
Environmental toxicology and pharmacology 2016 Jul;45:241-50
Small-Activating RNA Can Change Nucleosome Positioning in Human Fibroblasts.
Wang B, Sun J, Shi J, Guo Q, Tong X, Zhang J, Hu N, Hu Y
Journal of biomolecular screening 2016 Jul;21(6):634-42
Journal of biomolecular screening 2016 Jul;21(6):634-42
Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells.
Cheng YC, Huang CJ, Lee YJ, Tien LT, Ku WC, Chien R, Lee FK, Chien CC
Scientific reports 2016 Jul 22;6:30314
Scientific reports 2016 Jul 22;6:30314
Epigenetic reprogramming of human lung cancer cells with the extract of bovine parthenogenetic oocytes.
Wang Z, Dao R, Bao L, Dong Y, Wang H, Han P, Yue Y, Yu H
Journal of cellular and molecular medicine 2014 Sep;18(9):1807-15
Journal of cellular and molecular medicine 2014 Sep;18(9):1807-15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SOX2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SOX2. This antibody recognizes human, mouse, rat, zebrafish antigen. The SOX2 antibody has been validated for the following applications: ELISA, WB analysis.
