CABT-B12427

antibody from Creative Diagnostics

Targeting: KIR3DL1 AMB11, CD158E1, CD158e1/2, CD158e2, cl-11, cl-2, KIR, nkat3, NKB1, NKB1B

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12427

Provider

Creative Diagnostics

Product name

Mouse anti-Human KIR3DL1/DL2 monoclonal antibody, clone 6.244 [Biotin]

Antibody type

Monoclonal

Description

It recognozes subsets of HLA alleles. The family of killer immunoglobulin-like receptors (KIR) contributes to the regulation of NK cell-mediated cytotoxicity. Expression is found mainly on CD56dim CD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.

Reactivity

Human

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Antibody clone number

6.244

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.