Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16214-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16214-1-AP, RRID:AB_2131201
- Product name
- KLHL22 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KLHL22 antibody (Cat. #16214-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.
KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
SUMOylation Promotes Nuclear Import and Stabilization of Polo-like Kinase 1 to Support Its Mitotic Function.
Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis.
Kato K, Miya F, Oka Y, Mizuno S, Saitoh S
Journal of human genetics 2021 May;66(5):491-498
Journal of human genetics 2021 May;66(5):491-498
KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
Chen J, Ou Y, Yang Y, Li W, Xu Y, Xie Y, Liu Y
Nature 2018 May;557(7706):585-589
Nature 2018 May;557(7706):585-589
SUMOylation Promotes Nuclear Import and Stabilization of Polo-like Kinase 1 to Support Its Mitotic Function.
Wen D, Wu J, Wang L, Fu Z
Cell reports 2017 Nov 21;21(8):2147-2159
Cell reports 2017 Nov 21;21(8):2147-2159
Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis.
Zhuo X, Guo X, Zhang X, Jing G, Wang Y, Chen Q, Jiang Q, Liu J, Zhang C
The Journal of cell biology 2015 Aug 31;210(5):727-35
The Journal of cell biology 2015 Aug 31;210(5):727-35
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The KLHL22 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KLHL22. This antibody recognizes human, mouse, rat antigen. The KLHL22 antibody has been validated for the following applications: ELISA, WB analysis.