Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [121]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 60178-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60178-1-Ig, RRID:AB_10734459
- Product name
- BCL2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated BCL2 antibody (Cat. #60178-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4H8C6
- Vial size
- 20ul, 150ul
Submitted references Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways.
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study.
TFEB promotes BCL-2 expression by upregulating its promoter activity in the t(6;11) translocation renal cell carcinomas.
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.
Effects of Ganfule capsule on microbial and metabolic profiles in anti-hepatocellular carcinoma.
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy.
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Ampelopsin Inhibits Breast Cancer Cell Growth through Mitochondrial Apoptosis Pathway.
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway.
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
O-GlcNAc / Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress.
Calvatia Lilacina Extracts Exert Anti-Breast-Cancer Bioactivity through the Apoptosis Induction Dependent on Mitochondrial Reactive Oxygen Species and Caspase Activation.
A natural product, Piperlongumine (PL), increases tumor cells sensitivity to NK cell killing.
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Dynamin 3 overexpression suppresses the proliferation, migration and invasion of cervical cancer cells.
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Effects and mechanism of microRNA‑218 against lung cancer.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Histone deacetylase 10 exerts anti-tumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response.
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Structural analysis of Panax ginseng glycoproteins and its anti-oligoasthenozoospermia effect in vivo.
Acetylcholine ameliorated hypoxia-induced oxidative stress and apoptosis in trophoblast cells via p38 MAPK/NF-κB pathway.
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats.
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression.
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
The roles of SHANK1 in the development of colon cancer.
Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury.
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Cinnamaldehyde Enhances Antimelanoma Activity through Covalently Binding ENO1 and Exhibits a Promoting Effect with Dacarbazine.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Acetylcholine ameliorated TNF-α-induced primary trophoblast malfunction via muscarinic receptors†.
METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway.
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
High glucose causes apoptosis of rabbit corneal epithelial cells involving activation of PERK-eIF2α-CHOP-caspase-12 signaling pathway.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
Linc01105 acts as an oncogene in the development of neuroblastoma.
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
Rho GDP dissociation inhibitor α silencing attenuates silicosis by inhibiting RhoA/Rho kinase signalling.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Protective effects of Platycodon grandiflorus polysaccharides against apoptosis induced by carbonyl cyanide 3-chlorophenylhydrazone in 3D4/21 cells.
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture.
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
A targeted proteomics approach to the quantitative analysis of ERK/Bcl-2-mediated anti-apoptosis and multi-drug resistance in breast cancer.
Neuroprotective effect of ethyl acetate extract from gastrodia elata against transient focal cerebral ischemia in rats induced by middle cerebral artery occlusion.
Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer.
Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis.
Apoptosis-induced anti-tumor effect of Curcuma kwangsiensis polysaccharides against human nasopharyngeal carcinoma cells.
Zhang D, Man X, Li L, Tang J, Liu F
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways.
Zhang Y, Li Y, Wang Q, Zheng D, Feng X, Zhao W, Cai L, Zhang Q, Xu H, Fu H
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Liu Y, Liu P, Hu Y, Cao Y, Lu J, Yang Y, Lv H, Lian S, Xu B, Li S
Frontiers in molecular biosciences 2021;8:685993
Frontiers in molecular biosciences 2021;8:685993
Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
Zhang D, Li C, Zhang L, Li B, Wang Y, Wang R, Chen Z, Xu L, Liu T
Nutrition and cancer 2021;73(11-12):2491-2501
Nutrition and cancer 2021;73(11-12):2491-2501
Expression of Ubiquitin-specific protease 7 in oral squamous cell carcinoma promotes tumor cell proliferation and invasion.
Yang X, Jin J, Yang J, Zhou L, Mi S, Qi G
Genetics and molecular biology 2021;44(4):e20210058
Genetics and molecular biology 2021;44(4):e20210058
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844
Oxidative medicine and cellular longevity 2021;2021:8847844
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Zhang C, Suo M, Liu L, Qi Y, Zhang C, Xie L, Zheng X, Ma C, Li J, Yang J, Bu P
Oxidative medicine and cellular longevity 2021;2021:6668887
Oxidative medicine and cellular longevity 2021;2021:6668887
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Liu J, Wu Q, Yang T, Yang F, Guo T, Zhou Y, Han S, Luo Y, Guo T, Luo F, Lin Q
Oxidative medicine and cellular longevity 2021;2021:2637577
Oxidative medicine and cellular longevity 2021;2021:2637577
Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study.
Zhang P, Yu B, Jin X, Zhao T, Ye F, Liu X, Li P, Zheng X, Chen W, Li Q
International journal of nanomedicine 2021;16:4661-4674
International journal of nanomedicine 2021;16:4661-4674
TFEB promotes BCL-2 expression by upregulating its promoter activity in the t(6;11) translocation renal cell carcinomas.
Zhan HQ, Qin R, Li YL, Liu MM, Gan L
American journal of translational research 2021;13(8):8804-8818
American journal of translational research 2021;13(8):8804-8818
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
Zou N, Zhang X, Li S, Li Y, Zhao Y, Yang X, Zhu S
Journal of Cancer 2021;12(16):5013-5024
Journal of Cancer 2021;12(16):5013-5024
MicroRNA-455-5p Contributes to Cholangiocarcinoma Growth and Mediates Galangin's Anti-Tumor Effects.
Deng X, Zuo M, Pei Z, Xie Y, Yang Z, Zhang Z, Jiang M, Kuang D
Journal of Cancer 2021;12(15):4710-4721
Journal of Cancer 2021;12(15):4710-4721
Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway.
Chen L, Yi C, Li W, Tseng Y, Zhang J, Liu J
Journal of Cancer 2021;12(1):89-98
Journal of Cancer 2021;12(1):89-98
miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2.
Yang L, Li L, Chang P, Wei M, Chen J, Zhu C, Jia J
Frontiers in genetics 2021;12:690196
Frontiers in genetics 2021;12:690196
Elevated Serum FGG Levels Prognosticate and Promote the Disease Progression in Prostate Cancer.
Peng HH, Wang JN, Xiao LF, Yan M, Chen SP, Wang L, Yang K
Frontiers in genetics 2021;12:651647
Frontiers in genetics 2021;12:651647
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
Di Y, Jiang Y, Shen X, Liu J, Gao Y, Cai H, Sun X, Ning D, Liu B, Lei J, Jin S
Frontiers in oncology 2021;11:679348
Frontiers in oncology 2021;11:679348
Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.
Yang X, Yu X, Zhao Z, He Y, Zhang J, Su X, Sun N, Fan Z
Journal of Zhejiang University. Science. B 2021 Sept 15;22(9):746-756
Journal of Zhejiang University. Science. B 2021 Sept 15;22(9):746-756
Effects of Ganfule capsule on microbial and metabolic profiles in anti-hepatocellular carcinoma.
Xu F, Li H, Pan Y, Zeng Y, Li J, Li S
Journal of applied microbiology 2021 Sep 26;
Journal of applied microbiology 2021 Sep 26;
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
Ma S, Zhou J, Huang T, Zhang Z, Xing Q, Zhou X, Zhang K, Yao M, Cheng T, Wang X, Wen X, Guan F
Acta biomaterialia 2021 Sep 1;131:185-197
Acta biomaterialia 2021 Sep 1;131:185-197
Interleukin-38 Suppresses Cell Migration and Proliferation and Promotes Apoptosis of Colorectal Cancer Cell Through Negatively Regulating Extracellular Signal-Regulated Kinases Signaling.
Huang L, Zhang H, Zhao D, Hu H, Lu Z
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2021 Oct;41(10):375-384
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.
Zhou C, Liang Y, Zhou L, Yan Y, Liu N, Zhang R, Huang Y, Wang M, Tang Y, Ali DW, Wang Y, Michalak M, Chen XZ, Tang J
Autophagy 2021 Oct;17(10):3175-3195
Autophagy 2021 Oct;17(10):3175-3195
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer.
Fan X, Fu H, Xie N, Guo H, Fu T, Shan Y
Aging 2021 Oct 8;13(19):22830-22842
Aging 2021 Oct 8;13(19):22830-22842
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Li Z, Xiao Z, Feng Y, Wang Q, Teng M
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591
LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy.
Zhang Q, Li D, Dong X, Zhang X, Liu J, Peng L, Meng B, Hua Q, Pei X, Zhao L, Hu X, Zhang Y, Pan Z, Lu Y, Yang B
Science China. Life sciences 2021 Oct 14;
Science China. Life sciences 2021 Oct 14;
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Zhao S, Wang C, Lu P, Lou Y, Liu H, Wang T, Yang S, Bao Z, Han L, Liang X, Ma C, Gao L
Journal for immunotherapy of cancer 2021 Nov;9(12)
Journal for immunotherapy of cancer 2021 Nov;9(12)
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Yang J, Zhang M, Yang D, Ma Y, Tang Y, Xing M, Li L, Chen L, Jin Y, Ma C
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2021 Nov 6;:1-14
Autophagy 2021 Nov 6;:1-14
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2021 Nov 30;
Phytotherapy research : PTR 2021 Nov 30;
CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Deficiency Attenuates Heatstroke-Induced Intestinal Injury.
Cao Y, Fan M, Pei Y, Su L, Xiao W, Chen F, Huang J, Liu X, Gu Z, Zhang Z, Yuan F, Jiang Y, Han X
Inflammation 2021 Nov 29;
Inflammation 2021 Nov 29;
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2021 Nov 26;
Environmental toxicology 2021 Nov 26;
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Liu X, Yang J, Yang C, Huang X, Han M, Kang F, Li J
Cancer cell international 2021 Nov 25;21(1):622
Cancer cell international 2021 Nov 25;21(1):622
Ampelopsin Inhibits Breast Cancer Cell Growth through Mitochondrial Apoptosis Pathway.
Li Y, Zhou Y, Wang M, Lin X, Zhang Y, Laurent I, Zhong Y, Li J
Biological & pharmaceutical bulletin 2021 Nov 1;44(11):1738-1745
Biological & pharmaceutical bulletin 2021 Nov 1;44(11):1738-1745
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Pang JL, Huang FH, Zhang YH, Wu Y, Ge XM, Li S, Li X
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Toxicology and applied pharmacology 2021 Nov 1;430:115726
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Chen S, Xiao L, Peng H, Wang Z, Xie J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway.
Huang N, Cui X, Li W, Zhang C, Liu L, Li J
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Zhu S, Liu X, Xue M, Li Y, Cai D, Wang S, Zhang L
Journal of ginseng research 2021 Mar;45(2):295-304
Journal of ginseng research 2021 Mar;45(2):295-304
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species-mediated PI3K/AKT pathway.
Liu S, Hu J, Shi C, Sun L, Yan W, Song Y
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Journal of cellular and molecular medicine 2021 Jun;25(12):5511-5524
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Zhang Z, Qin X, Wang Z, Li Y, Chen F, Chen R, Li C, Zhang W, Zhang M
Experimental and therapeutic medicine 2021 Jun;21(6):556
Experimental and therapeutic medicine 2021 Jun;21(6):556
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
Ma Y, Yang X, Han H, Wen Z, Yang M, Zhang Y, Fu J, Wang X, Yin T, Lu G, Qi J, Lin H, Wang X, Yang Y
Bioorganic chemistry 2021 Jun;111:104872
Bioorganic chemistry 2021 Jun;111:104872
O-GlcNAc / Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress.
Liu Y, Xu B, Hu Y, Liu P, Lian S, Lv H, Yang Y, Ji H, Yang H, Liu J, Yao R, Li S
Cryobiology 2021 Jun;100:125-132
Cryobiology 2021 Jun;100:125-132
Calvatia Lilacina Extracts Exert Anti-Breast-Cancer Bioactivity through the Apoptosis Induction Dependent on Mitochondrial Reactive Oxygen Species and Caspase Activation.
Zeng Q, Singh R, Ye Y, Cheng S, Fan C, Zeng Q
Nutrition and cancer 2021 Jun 12;:1-13
Nutrition and cancer 2021 Jun 12;:1-13
A natural product, Piperlongumine (PL), increases tumor cells sensitivity to NK cell killing.
Afolabi LO, Bi J, Chen L, Wan X
International immunopharmacology 2021 Jul;96:107658
International immunopharmacology 2021 Jul;96:107658
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454
Molecular carcinogenesis 2021 Jul;60(7):440-454
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Dynamin 3 overexpression suppresses the proliferation, migration and invasion of cervical cancer cells.
Fa J
Oncology letters 2021 Jul;22(1):524
Oncology letters 2021 Jul;22(1):524
BACH1 is transcriptionally inhibited by TET1 in hepatocellular carcinoma in a microRNA-34a-dependent manner to regulate autophagy and inflammation.
Sun X, Zhu H, Cao R, Zhang J, Wang X
Pharmacological research 2021 Jul;169:105611
Pharmacological research 2021 Jul;169:105611
HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation.
Shao Y, Zhu F, Zhu S, Bai L
The international journal of biochemistry & cell biology 2021 Jul;136:106000
The international journal of biochemistry & cell biology 2021 Jul;136:106000
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Li P, Liu X, Zhao T, Li F, Wang Q, Zhang P, Hirayama R, Chen W, Jin X, Zheng X, Wang Z, Li Q
Cell death discovery 2021 Jul 20;7(1):184
Cell death discovery 2021 Jul 20;7(1):184
Effects and mechanism of microRNA‑218 against lung cancer.
Chen Y, Yang JL, Xue ZZ, Cai QC, Hou C, Li HJ, Zhao LX, Zhang Y, Gao CW, Cong L, Wang TZ, Chen DM, Li GS, Luo SQ, Yao Q, Yang CJ, Zhu QS, Cao CH
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
Histone deacetylase 10 exerts anti-tumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
Zhu J, Han S
IUBMB life 2021 Jan 22;
IUBMB life 2021 Jan 22;
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways.
Zhou S, Dai Z, Wang L, Gao X, Yang L, Wang Z, Wang Q, Liu Z
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Journal of cellular and molecular medicine 2021 Dec;25(24):11157-11169
Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response.
Li Z, Wang Q, Li L, Chen Y, Cui J, Liu M, Zhang N, Liu Z, Han J, Wang Z
Journal of medicinal chemistry 2021 Dec 23;64(24):17920-17935
Journal of medicinal chemistry 2021 Dec 23;64(24):17920-17935
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Wang K, Li Z, Sun Y, Liu X, Ma W, Ding Y, Hong J, Qian L, Xu D
Journal of cardiovascular translational research 2021 Dec 2;
Journal of cardiovascular translational research 2021 Dec 2;
Structural analysis of Panax ginseng glycoproteins and its anti-oligoasthenozoospermia effect in vivo.
Shan M, Zhang X, Fang X, Tian J, Song L, Chen Y, Qiu Z, Zhu D, Luo H, Wang Z
International journal of biological macromolecules 2021 Dec 15;193(Pt A):778-788
International journal of biological macromolecules 2021 Dec 15;193(Pt A):778-788
Acetylcholine ameliorated hypoxia-induced oxidative stress and apoptosis in trophoblast cells via p38 MAPK/NF-κB pathway.
Wang Z, Zhao G, Zibrila AI, Li Y, Liu J, Feng W
Molecular human reproduction 2021 Aug 7;27(8)
Molecular human reproduction 2021 Aug 7;27(8)
circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway.
Bian Q, Chen B, Weng B, Chu D, Tang X, Yan S, Yin Y, Ran M
International journal of molecular sciences 2021 Aug 30;22(17)
International journal of molecular sciences 2021 Aug 30;22(17)
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2021 Aug 28;
Cell biology and toxicology 2021 Aug 28;
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA-223/TXNIP/Wnt/β-catenin pathway.
Zhu J, Han S
IUBMB life 2021 Apr;73(4):690-704
IUBMB life 2021 Apr;73(4):690-704
Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats.
Fan H, Ding R, Liu W, Zhang X, Li R, Wei B, Su S, Jin F, Wei C, He X, Li X, Duan C
Redox biology 2021 Apr;40:101856
Redox biology 2021 Apr;40:101856
Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells.
Chen J, Zhang W, Pan C, Fan J, Zhong X, Tang S
Life sciences 2021 Apr 15;271:119185
Life sciences 2021 Apr 15;271:119185
Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo.
Wang CH, Yang JM, Guo YB, Shen J, Pei XH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6823520
Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression.
Zou Y, Li R, Kuang D, Zuo M, Li W, Tong W, Jiang L, Zhou M, Chen Y, Gong W, Liu L, Tou F
BioMed research international 2020;2020:5846938
BioMed research international 2020;2020:5846938
Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy.
Zhang Y, Huang N, Xu J, Zheng W, Cui X
Drug design, development and therapy 2020;14:4749-4763
Drug design, development and therapy 2020;14:4749-4763
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
Li Q, Ma Y, Liu XL, Mu L, He BC, Wu K, Sun WJ
Oncology reports 2020 Nov;44(5):2093-2107
Oncology reports 2020 Nov;44(5):2093-2107
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M
Bioorganic chemistry 2020 Mar;96:103592
Bioorganic chemistry 2020 Mar;96:103592
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Lin Y, Yu M, Fan T
Toxicology letters 2020 Mar 1;320:9-18
Toxicology letters 2020 Mar 1;320:9-18
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
The roles of SHANK1 in the development of colon cancer.
Wang L, Lv Y, Liu G
Cell biochemistry and function 2020 Jul;38(5):669-675
Cell biochemistry and function 2020 Jul;38(5):669-675
Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury.
Hu X, Li R, Wu Y, Li Y, Zhong X, Zhang G, Kang Y, Liu S, Xie L, Ye J, Xiao J
Journal of cellular and molecular medicine 2020 Jul;24(14):8166-8178
Journal of cellular and molecular medicine 2020 Jul;24(14):8166-8178
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Niu Q, Sun W, Chen Q, Long Y, Cao W, Wen S, Li A, Dong F, Shi H
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
Cinnamaldehyde Enhances Antimelanoma Activity through Covalently Binding ENO1 and Exhibits a Promoting Effect with Dacarbazine.
Zhang W, Gao J, Cheng C, Zhang M, Liu W, Ma X, Lei W, Hao E, Hou X, Hou Y, Bai G
Cancers 2020 Jan 29;12(2)
Cancers 2020 Jan 29;12(2)
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
Human cathelicidin antimicrobial peptide suppresses proliferation, migration and invasion of oral carcinoma HSC-3 cells via a novel mechanism involving caspase-3 mediated apoptosis.
Chen X, Ji S, Si J, Zhang X, Wang X, Guo Y, Zou X
Molecular medicine reports 2020 Dec;22(6):5243-5250
Molecular medicine reports 2020 Dec;22(6):5243-5250
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis.
Bi HQ, Li ZH, Zhang H
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
Hepatobiliary & pancreatic diseases international : HBPD INT 2020 Dec;19(6):567-574
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.
Li L, He Y, He XJ, Bi MR, Qi YH, Zhu WW
Experimental and molecular pathology 2020 Dec;117:104562
Experimental and molecular pathology 2020 Dec;117:104562
Acetylcholine ameliorated TNF-α-induced primary trophoblast malfunction via muscarinic receptors†.
Wang Z, Zibrila AI, Liu S, Zhao G, Li Y, Xu J, Liu D, Li C, Feng W, Liu J
Biology of reproduction 2020 Dec 1;103(6):1238-1248
Biology of reproduction 2020 Dec 1;103(6):1238-1248
METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway.
Liang S, Guan H, Lin X, Li N, Geng F, Li J
Oncology letters 2020 Apr;19(4):3197-3204
Oncology letters 2020 Apr;19(4):3197-3204
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
Yang K, Lu T, Zhan L, Zhou C, Zhang N, Lei S, Wang Y, Yang J, Yan M, Lv G, Chen S
International journal of biological macromolecules 2020 Apr 15;149:320-330
International journal of biological macromolecules 2020 Apr 15;149:320-330
High glucose causes apoptosis of rabbit corneal epithelial cells involving activation of PERK-eIF2α-CHOP-caspase-12 signaling pathway.
Yao PP, Sheng MJ, Weng WH, Long Y, Liu H, Chen L, Lu JJ, Rong A, Li B
International journal of ophthalmology 2019;12(12):1815-1822
International journal of ophthalmology 2019;12(12):1815-1822
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
He Z, Du X, Wu Y, Hua L, Wan L, Yan N
International journal of molecular medicine 2019 Oct;44(4):1289-1298
International journal of molecular medicine 2019 Oct;44(4):1289-1298
Linc01105 acts as an oncogene in the development of neuroblastoma.
Ye M, Ma J, Liu B, Liu X, Ma D, Dong K
Oncology reports 2019 Oct;42(4):1527-1538
Oncology reports 2019 Oct;42(4):1527-1538
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Zhang L, Wang F, Zhang Q, Liang Q, Wang S, Xian M, Wang F
International journal of molecular sciences 2019 Oct 29;20(21)
International journal of molecular sciences 2019 Oct 29;20(21)
Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway.
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, Cui H, Xiao Y
Molecular medicine reports 2019 Nov;20(5):4551-4557
Molecular medicine reports 2019 Nov;20(5):4551-4557
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang YY, Yang H, Li S
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice.
Liu P, Yao R, Shi H, Liu Y, Lian S, Yang Y, Yang H, Li S
International journal of molecular sciences 2019 Mar 23;20(6)
International journal of molecular sciences 2019 Mar 23;20(6)
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
Hua L, Wu N, Zhao R, He X, Liu Q, Li X, He Z, Yu L, Yan N
International journal of molecular sciences 2019 Jun 12;20(12)
International journal of molecular sciences 2019 Jun 12;20(12)
Rho GDP dissociation inhibitor α silencing attenuates silicosis by inhibiting RhoA/Rho kinase signalling.
Wei Z, Xu H, Zhang Y, Yi X, Yang X, Chen Y, Mao N, Li S, Xu D, Li S, Zhang H, Li D, Zhang G, Zhang B, Jin F, Gao X, Cai W, Zhang L, Wang R, Yang F
Experimental cell research 2019 Jul 15;380(2):131-140
Experimental cell research 2019 Jul 15;380(2):131-140
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway.
Li L, Liu M, Zhang Z, Zhang W, Liu N, Sheng X, Wei P
Biological research 2019 Feb 27;52(1):8
Biological research 2019 Feb 27;52(1):8
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
Protective effects of Platycodon grandiflorus polysaccharides against apoptosis induced by carbonyl cyanide 3-chlorophenylhydrazone in 3D4/21 cells.
Wang C, Cheng G, Yang S, Li L, Zhang Y, Zhao X, Liu J
International journal of biological macromolecules 2019 Dec 1;141:1220-1227
International journal of biological macromolecules 2019 Dec 1;141:1220-1227
MicroRNA-2053 overexpression inhibits the development and progression of hepatocellular carcinoma.
Song T, Ma K, Zhao C, Yang J, Liu J
Oncology letters 2019 Aug;18(2):2043-2049
Oncology letters 2019 Aug;18(2):2043-2049
CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.
Li K, Meng Z, Jiang L, Xia C, Xu K, Yuan D, Chen H, Zhang B, Liu S
Molecular and cellular probes 2019 Apr;44:57-62
Molecular and cellular probes 2019 Apr;44:57-62
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling.
Yin Y, Xu M, Gao J, Li M
Pathology, research and practice 2018 Sep;214(9):1381-1387
Pathology, research and practice 2018 Sep;214(9):1381-1387
UNBS5162 inhibits proliferation of human melanoma cells by inducing apoptosis via the PI3K/Akt pathway.
Shi X, Yang L, Xie J, Zhao Y, Cong J, Li Z, Li H, Cheng X, Fan J
Molecular medicine reports 2018 Sep;18(3):3382-3388
Molecular medicine reports 2018 Sep;18(3):3382-3388
Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice.
Yao R, Yang Y, Lian S, Shi H, Liu P, Liu Y, Yang H, Li S
International journal of molecular sciences 2018 Sep 18;19(9)
International journal of molecular sciences 2018 Sep 18;19(9)
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Lu K, Rui G, Liu F, Yang L, Deng X, Shi S, Li Q
Oncology letters 2018 Jan;15(1):338-346
Oncology letters 2018 Jan;15(1):338-346
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773
Cancer science 2018 Dec;109(12):3762-3773
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M, Chen Y, Jia J, Li L, Yang S
Biological research 2018 Aug 10;51(1):24
Biological research 2018 Aug 10;51(1):24
Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture.
Zhang Z, Wen F, He C, Yu J
Bioscience reports 2018 Apr 27;38(2)
Bioscience reports 2018 Apr 27;38(2)
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma.
Yang F, Shi L, Liang T, Ji L, Zhang G, Shen Y, Zhu F, Xu L
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Biochemical and biophysical research communications 2017 Mar 25;485(1):54-61
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
Li B, Hou D, Guo H, Zhou H, Zhang S, Xu X, Liu Q, Zhang X, Zou Y, Gong Y, Shao C
Scientific reports 2017 Mar 16;7(1):208
Scientific reports 2017 Mar 16;7(1):208
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
A targeted proteomics approach to the quantitative analysis of ERK/Bcl-2-mediated anti-apoptosis and multi-drug resistance in breast cancer.
Yang T, Xu F, Sheng Y, Zhang W, Chen Y
Analytical and bioanalytical chemistry 2016 Oct;408(26):7491-503
Analytical and bioanalytical chemistry 2016 Oct;408(26):7491-503
Neuroprotective effect of ethyl acetate extract from gastrodia elata against transient focal cerebral ischemia in rats induced by middle cerebral artery occlusion.
Duan X, Wang W, Liu X, Yan H, Dai R, Lin Q
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2015 Dec;35(6):671-8
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2015 Dec;35(6):671-8
Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer.
Sun Y, Liu Z, Zou X, Lan Y, Sun X, Wang X, Zhao S, Jiang C, Liu H
Journal of bioenergetics and biomembranes 2015 Aug;47(4):319-29
Journal of bioenergetics and biomembranes 2015 Aug;47(4):319-29
Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis.
Liu C, Hong T, Shao M, Chen Z, Wang C
Molecular medicine reports 2014 Sep;10(3):1323-8
Molecular medicine reports 2014 Sep;10(3):1323-8
Apoptosis-induced anti-tumor effect of Curcuma kwangsiensis polysaccharides against human nasopharyngeal carcinoma cells.
Zeng J, Dai P, Ren L, Song B, Chen X, Wang X, Wang J, Zhang T, Zhu W
Carbohydrate polymers 2012 Aug 1;89(4):1067-72
Carbohydrate polymers 2012 Aug 1;89(4):1067-72
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 60178-1-Ig(BCL2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BCL2 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human BCL2. This antibody recognizes human antigen. The BCL2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
