Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6953 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IFN R2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human IFN-R2.
- Description
- The type I interferons, IFN-Ï« and IFN-ÉÇ, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-Ï« and IFN-ÉÇ appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-ÎÛ) binds to a distinct receptor. This distinct receptor, IFN-Ï«R, is only weakly responsive to type I interferons, in contrast to IFN-Ï«/ÉÇR, which binds to and responds effectively to IFN-ÉÇ and to several of the IFN-Ï« subtypes. IFN-Ï«/ÉÇR is expressed as two alternatively spliced transcripts, designated IFN-Ï«/ÉÇRÏ« (IFN-Ï«/ÉÇR1) and IFN-Ï«/ÉÇRÉÇ (IFN-Ï«/ÉÇR2), both of which are involved in signal transduction and ligand binding.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of IFN-R2 polyclonal antibody