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antibody from Novus Biologicals
Targeting: TLR9
CD289
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ELISA Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Functional assayAntibody data
- Antibody Data
- Antigen structure
- References [56]
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- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [7]
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- Product number
- NBP2-24863 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TLR9 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response.
Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer.
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum.
TLR4 and TLR9 are induced in oral lichen planus.
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis.
Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes.
Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle.
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection.
TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides.
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula.
Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response.
Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9.
Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis.
TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients.
Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer.
Toll-like receptor expression in normal ovary and ovarian tumors.
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation.
Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6.
Expression of TLR9 within human glioblastoma.
Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
Human lymphatic endothelial cells express multiple functional TLRs.
Human lymphatic endothelial cells express multiple functional TLRs.
Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry.
Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus.
Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa.
Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS.
Molecular cloning and characterization of equine Toll-like receptor 9.
CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands.
Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.
Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation.
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides.
Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells.
Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha.
Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells.
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Human lung cancer cells express functionally active Toll-like receptor 9.
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
Evidence of Toll-like receptor molecules on human platelets.
Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.
Guerrier T, Pochard P, Lahiri A, Youinou P, Pers JO, Jamin C
Journal of autoimmunity 2014 Jun;51:23-9
Journal of autoimmunity 2014 Jun;51:23-9
Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer.
Belmont L, Rabbe N, Antoine M, Cathelin D, Guignabert C, Kurie J, Cadranel J, Wislez M
International journal of cancer 2014 Feb 15;134(4):765-77
International journal of cancer 2014 Feb 15;134(4):765-77
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Abdi J, Mutis T, Garssen J, Redegeld F
PloS one 2013;8(4):e60671
PloS one 2013;8(4):e60671
Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum.
Figueiredo MM, Amorim IF, Pinto AJ, Barbosa VS, Pinheiro Lde J, Deoti B, Faria AM, Tafuri WL
BMC immunology 2013 May 14;14:22
BMC immunology 2013 May 14;14:22
TLR4 and TLR9 are induced in oral lichen planus.
Siponen M, Kauppila JH, Soini Y, Salo T
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Nov;41(10):741-7
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Nov;41(10):741-7
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn AB, BenMohamed L
Investigative ophthalmology & visual science 2011 May 17;52(6):3321-33
Investigative ophthalmology & visual science 2011 May 17;52(6):3321-33
Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis.
Myles A, Aggarwal A
Rheumatology (Oxford, England) 2011 Mar;50(3):481-8
Rheumatology (Oxford, England) 2011 Mar;50(3):481-8
Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes.
Karim R, Meyers C, Backendorf C, Ludigs K, Offringa R, van Ommen GJ, Melief CJ, van der Burg SH, Boer JM
PloS one 2011 Mar 14;6(3):e17848
PloS one 2011 Mar 14;6(3):e17848
Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle.
Schneberger D, Lewis D, Caldwell S, Singh B
International journal of experimental pathology 2011 Feb;92(1):1-7
International journal of experimental pathology 2011 Feb;92(1):1-7
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection.
van Gent M, Griffin BD, Berkhoff EG, van Leeuwen D, Boer IG, Buisson M, Hartgers FC, Burmeister WP, Wiertz EJ, Ressing ME
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 1;186(3):1694-702
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 1;186(3):1694-702
TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides.
Booth JS, Arsenault R, Napper S, Griebel PJ, Potter AA, Babiuk LA, Mutwiri GK
Journal of innate immunity 2010;2(5):483-94
Journal of innate immunity 2010;2(5):483-94
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.
Chentoufi AA, Dasgupta G, Nesburn AB, Bettahi I, Binder NR, Choudhury ZS, Chamberlain WD, Wechsler SL, BenMohamed L
Clinical and vaccine immunology : CVI 2010 Mar;17(3):342-53
Clinical and vaccine immunology : CVI 2010 Mar;17(3):342-53
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF
Immunology 2010 Mar;129(3):363-74
Immunology 2010 Mar;129(3):363-74
Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula.
Kim YI, Park JE, Brand DD, Fitzpatrick EA, Yi AK
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3145-56
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3145-56
Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response.
Panda A, Qian F, Mohanty S, van Duin D, Newman FK, Zhang L, Chen S, Towle V, Belshe RB, Fikrig E, Allore HG, Montgomery RR, Shaw AC
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2518-27
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 1;184(5):2518-27
Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9.
Keestra AM, de Zoete MR, Bouwman LI, van Putten JP
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 1;185(1):460-7
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 1;185(1):460-7
Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis.
Machida H, Ito S, Hirose T, Takeshita F, Oshiro H, Nakamura T, Mori M, Inayama Y, Yan K, Kobayashi N, Yokota S
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010 Aug;25(8):2530-537
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010 Aug;25(8):2530-537
TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients.
Wang C, Cao S, Yan Y, Ying Q, Jiang T, Xu K, Wu A
BMC cancer 2010 Aug 10;10:415
BMC cancer 2010 Aug 10;10:415
Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer.
Jukkola-Vuorinen A, Rahko E, Vuopala KS, Desmond R, Lehenkari PP, Harris KW, Selander KS
Journal of innate immunity 2009;1(1):59-68
Journal of innate immunity 2009;1(1):59-68
Toll-like receptor expression in normal ovary and ovarian tumors.
Zhou M, McFarland-Mancini MM, Funk HM, Husseinzadeh N, Mounajjed T, Drew AF
Cancer immunology, immunotherapy : CII 2009 Sep;58(9):1375-85
Cancer immunology, immunotherapy : CII 2009 Sep;58(9):1375-85
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
Cohen PA, Koski GK, Czerniecki BJ, Bunting KD, Fu XY, Wang Z, Zhang WJ, Carter CS, Awad M, Distel CA, Nagem H, Paustian CC, Johnson TD, Tisdale JF, Shu S
Blood 2008 Sep 1;112(5):1832-43
Blood 2008 Sep 1;112(5):1832-43
TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation.
Meneghin A, Choi ES, Evanoff HL, Kunkel SL, Martinez FJ, Flaherty KR, Toews GB, Hogaboam CM
Histochemistry and cell biology 2008 Nov;130(5):979-92
Histochemistry and cell biology 2008 Nov;130(5):979-92
Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6.
Cognasse F, Hamzeh-Cognasse H, Lafarge S, Chavarin P, Pozzetto B, Richard Y, Garraud O
Immunology 2008 Nov;125(3):430-7
Immunology 2008 Nov;125(3):430-7
Expression of TLR9 within human glioblastoma.
Meng Y, Kujas M, Marie Y, Paris S, Thillet J, Delattre JY, Carpentier AF
Journal of neuro-oncology 2008 May;88(1):19-25
Journal of neuro-oncology 2008 May;88(1):19-25
Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M, Kawakami K
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 15;180(6):4067-74
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 15;180(6):4067-74
Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M, Kawakami K
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 15;180(6):4067-74
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 15;180(6):4067-74
Human lymphatic endothelial cells express multiple functional TLRs.
Pegu A, Qin S, Fallert Junecko BA, Nisato RE, Pepper MS, Reinhart TA
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Human lymphatic endothelial cells express multiple functional TLRs.
Pegu A, Qin S, Fallert Junecko BA, Nisato RE, Pepper MS, Reinhart TA
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry.
Burgener IA, Jungi TW
Veterinary immunology and immunopathology 2008 Jul 15;124(1-2):184-91
Veterinary immunology and immunopathology 2008 Jul 15;124(1-2):184-91
Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus.
Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, Takasaki Y
Rheumatology (Oxford, England) 2008 Feb;47(2):145-9
Rheumatology (Oxford, England) 2008 Feb;47(2):145-9
Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa.
Palladino MA, Savarese MA, Chapman JL, Dughi MK, Plaska D
American journal of reproductive immunology (New York, N.Y. : 1989) 2008 Dec;60(6):541-55
American journal of reproductive immunology (New York, N.Y. : 1989) 2008 Dec;60(6):541-55
Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS.
Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola FM, Rumio C
International immunology 2008 Aug;20(8):961-70
International immunology 2008 Aug;20(8):961-70
Molecular cloning and characterization of equine Toll-like receptor 9.
Zhang YW, Davis EG, Blecha F, Wilkerson MJ
Veterinary immunology and immunopathology 2008 Aug 15;124(3-4):209-19
Veterinary immunology and immunopathology 2008 Aug 15;124(3-4):209-19
CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands.
Ju X, Zenke M, Hart DN, Clark GJ
Blood 2008 Aug 15;112(4):1184-94
Blood 2008 Aug 15;112(4):1184-94
Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.
Ewaschuk JB, Backer JL, Churchill TA, Obermeier F, Krause DO, Madsen KL
Infection and immunity 2007 May;75(5):2572-9
Infection and immunity 2007 May;75(5):2572-9
Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.
Kindrachuk J, Potter JE, Brownlie R, Ficzycz AD, Griebel PJ, Mookherjee N, Mutwiri GK, Babiuk LA, Napper S
The Journal of biological chemistry 2007 May 11;282(19):13944-53
The Journal of biological chemistry 2007 May 11;282(19):13944-53
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Palladino MA, Johnson TA, Gupta R, Chapman JL, Ojha P
Biology of reproduction 2007 Jun;76(6):958-64
Biology of reproduction 2007 Jun;76(6):958-64
Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation.
Tran N, Koch A, Berkels R, Boehm O, Zacharowski PA, Baumgarten G, Knuefermann P, Schott M, Kanczkowski W, Bornstein SR, Lightman SL, Zacharowski K
The Journal of clinical endocrinology and metabolism 2007 Jul;92(7):2773-83
The Journal of clinical endocrinology and metabolism 2007 Jul;92(7):2773-83
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides.
Martin-Armas M, Simon-Santamaria J, Pettersen I, Moens U, Smedsrød B, Sveinbjørnsson B
Journal of hepatology 2006 May;44(5):939-46
Journal of hepatology 2006 May;44(5):939-46
Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.
Damiano V, Caputo R, Bianco R, D'Armiento FP, Leonardi A, De Placido S, Bianco AR, Agrawal S, Ciardiello F, Tortora G
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jan 15;12(2):577-83
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Jan 15;12(2):577-83
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B
Nature immunology 2006 Feb;7(2):156-64
Nature immunology 2006 Feb;7(2):156-64
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Lee J, Wu CC, Lee KJ, Chuang TH, Katakura K, Liu YT, Chan M, Tawatao R, Chung M, Shen C, Cottam HB, Lai MM, Raz E, Carson DA
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
Mansson A, Adner M, Cardell LO
Respiratory research 2006 Feb 27;7:36
Respiratory research 2006 Feb 27;7:36
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.
Gottenberg JE, Cagnard N, Lucchesi C, Letourneur F, Mistou S, Lazure T, Jacques S, Ba N, Ittah M, Lepajolec C, Labetoulle M, Ardizzone M, Sibilia J, Fournier C, Chiocchia G, Mariette X
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 21;103(8):2770-5
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 21;103(8):2770-5
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells.
Lee J, Mo JH, Katakura K, Alkalay I, Rucker AN, Liu YT, Lee HK, Shen C, Cojocaru G, Shenouda S, Kagnoff M, Eckmann L, Ben-Neriah Y, Raz E
Nature cell biology 2006 Dec;8(12):1327-36
Nature cell biology 2006 Dec;8(12):1327-36
Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha.
Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM
Circulation 2006 Dec 5;114(23):2482-9
Circulation 2006 Dec 5;114(23):2482-9
Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells.
Abel K, Wang Y, Fritts L, Sanchez E, Chung E, Fitzgerald-Bocarsly P, Krieg AM, Miller CJ
Clinical and diagnostic laboratory immunology 2005 May;12(5):606-21
Clinical and diagnostic laboratory immunology 2005 May;12(5):606-21
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI
Leukemia research 2005 Jul;29(7):813-20
Leukemia research 2005 Jul;29(7):813-20
Human lung cancer cells express functionally active Toll-like receptor 9.
Droemann D, Albrecht D, Gerdes J, Ulmer AJ, Branscheid D, Vollmer E, Dalhoff K, Zabel P, Goldmann T
Respiratory research 2005 Jan 4;6:1
Respiratory research 2005 Jan 4;6:1
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S, O'neill SJ, McElvaney NG
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S, O'neill SJ, McElvaney NG
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
Evidence of Toll-like receptor molecules on human platelets.
Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O
Immunology and cell biology 2005 Apr;83(2):196-8
Immunology and cell biology 2005 Apr;83(2):196-8
Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.
Lee HK, Dunzendorfer S, Tobias PS
The Journal of biological chemistry 2004 Mar 12;279(11):10564-74
The Journal of biological chemistry 2004 Mar 12;279(11):10564-74
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TLR9 Antibody (26C593.2) [Azide Free] [NBP2-24863] - Analysis of TLR9 in A) human PBMC, B) human intestine, C) mouse intestine, and D) rat intestine tissue lysates using this antibody at a dilution of 3 ug/ml.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Simple Western lane view shows a specific band for TLR9 in 0.5 mg/ml of Ramos lysate. This experiment was performed under reducing conditions using the 66-440 kDa separation system.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TLR9 Antibody (26C593.2) [Azide Free] [NBP2-24863] - Formalin-fixed, paraffin-embedded human spleen probed with TLR9 antibody at 5 ug/ml. Human tissue was used for this test. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) [Azide Free] [NBP2-24863] - Intracellular flow analysis of TLR9 in Ramos cells using 0.5 ug of this antibody. Shaded histogram represents Ramos cells without antibody; green represents isotype control; purple represents anti-TLR9 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Intracellular flow cytometric analysis of TLR9 FITC in human B cells using 1ug/10^6 cells of NBP2-24908. Cells were primarily stained with PE-conjugated CD19 antibody. Cells were then fixed and permeabilized and stained with 1ug of either isotype control
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Intracellular): TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Analysis using the PE conjugate of NBP2-24729. Staining of TLR9 in human PBMCs using 0.2 ug of this antibody. Shaded histogram represents cells without antibody; green represents a mouse IgG1-PE isotype control ; red represents anti-TLR9 antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Analysis using the Azide Free version of NBP2-24729. Staining of TLR9 in Ramos cells using 0.5 ug of this antibody. Shaded histogram represents Ramos cells without antibody; green represents isotype control; purple represents anti-TLR9 antibody.
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Analysis using the FITC conjugate of NBP2-24729. Staining of TLR9 in Ramos cells using 0.5 ug of this antibody. Green represents isotype control ; red represents anti-TLR9 antibody. TLR intracellular flow kit was used for this test.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863] - Flow analysis of TLR9 in human PBMC using 0.5 ug of TLR9 antibody (red) and isotype control antibody (green).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR9 Antibody (26C593.2) - Azide Free [NBP2-24863]
