MAB0087

antibody from Abnova Corporation

Targeting: TLR9 CD289

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB0087

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB0087, RRID:AB_1017051

Product name

TLR9 monoclonal antibody, clone 26C593.2

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against synthetic peptide of TLR9.

Isotype

IgG

Antibody clone number

26C593.2

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Activation of TLR9-dependent p38MAPK pathway in the pathogenesis of primary Sjögren's syndrome in NOD/Ltj mouse.

Shi H, Yu CQ, Xie LS, Wang ZJ, Zhang P, Zheng LY
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Nov;43(10):785-91

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TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation.

Meneghin A, Choi ES, Evanoff HL, Kunkel SL, Martinez FJ, Flaherty KR, Toews GB, Hogaboam CM
Histochemistry and cell biology 2008 Nov;130(5):979-92

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Expression of TLR9 within human glioblastoma.

Meng Y, Kujas M, Marie Y, Paris S, Thillet J, Delattre JY, Carpentier AF
Journal of neuro-oncology 2008 May;88(1):19-25

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Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus.

Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, Takasaki Y
Rheumatology (Oxford, England) 2008 Feb;47(2):145-9

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Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS.

Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola FM, Rumio C
International immunology 2008 Aug;20(8):961-70

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Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation.

Tran N, Koch A, Berkels R, Boehm O, Zacharowski PA, Baumgarten G, Knuefermann P, Schott M, Kanczkowski W, Bornstein SR, Lightman SL, Zacharowski K
The Journal of clinical endocrinology and metabolism 2007 Jul;92(7):2773-83

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of TLR9 in A) human PBMC, B) human intestine, C) mouse intestine and D) rat intestine tissue lysates using TLR9 monoclonal antibody, clone 26C593.2 (Cat # MAB0087) at 3 ug/mL .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

IHC analysis of TLR9 monoclonal antibody, clone 26C593.2 (Cat # MAB0087) in adenocarcinoma of the lung (A) , A-549 cells (C) , and malignant lung tissues (F) at 1 : 100 dilution.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Flow cytometry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Intracellular flow analysis of TLR9 in Ramos cells. Using 0.1 ug of TLR9 monoclonal antibody, clone 26C593.2 (Cat # MAB0087). Shaded histogram represents Ramos cells without antibody; Green represents isotype control ; red represents anti-TLR9 antibody.

Validation comment

Flow Cytometry